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020			_a 1420004336
020			_a9781420004335
040			_cDLC
082			_a616.8 LEV
100			_a Edward D. Levin _941511
222			_aacetylcholine acquisition agonist Alzheimer’s disease amygdala amyloid animal models antagonist Aroclor assessed attention Behav behavior brain injury Brain Res choice cholinergic cognitive cognitive deficits cognitive function cognitive impairment cortex cortical cues delay developmental discrimination reversal disruption dopamine dose drug dysfunction effects of ethanol ethanol exposed fear conditioning foot shock gene genetic gestation goldfish hippocampus human increased inhibition interval knockout latency lead exposure learning and memory lesions lever pressing Levin M1 mAChR mAChR KO mice mecamylamine MeHg memory deficits memory impairment methylmercury mg/kg monkeys Morris water maze motor mouse MPTP muscarinic mutant nAChR neural neurons Neurosci Neurotoxicol nicotinic nicotinic acetylcholine receptor NMDA receptor nonspatial observed PCB exposure performance Pharmacol pharmacological phenotype potential processes Psychopharmacology radial arm maze rats reinforcement response retention rodents role schedule schizophrenia scopolamine sensitivity session spatial learning stimulus studies task Teratol Toxicol transgenic transgenic mice trials visual zebrafish
245			_aAnimal Models of Cognitive Impairment _bFrontiers in Neuroscience
250			_a illustrated
260			_aLondon _b CRC Press _c2006
300			_a 400 pages
505			_aContents: 1 Introduction 2 Muscarinic Receptor Antagonists in Rats 3 Nicotinic Receptor Antagonists in Rats 4 Involvement of the NMDA System in Learning and Memory 5 Animal Models and the Cognitive Effects of Ethanol 6 Animal Models of Cognitive Impairment Produced by Developmental Lead Exposure Consequences Conditioning and Cortex What Animal Models Have Told Us 9 Modeling Cognitive Deficits Associated with Parkinsonism in the ChronicLowDose MPTPTreated Monkey 10 Cognitive Impairment in Transgenic Mouse Models of Amyloid Deposition 11 Cholinergic Receptor Knockout Mice 12 Assessments of Cognitive Deficits in Mutant Mice 13 Cognitive Pharmacology in Aging Macaques 14 Cognitive Impairment following Traumatic Brain Injury 15 Cognitive Impairment Models Using Complementary Species 16 Cognition Models and Drug Discovery Index
520			_a The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen
600			_x Science › Life Sciences › General _927776
600			_x Medical / Neurology _926948
600			_xScience / Life Sciences / General _927324
600			_xTechnology & Engineering / Agriculture / General _938950
600			_xScience / Life Sciences / Neuroscience _927050
700			_aJerry J. Buccafusco _941512
942			_2ddc _cEB
999			_c8201 _d8201