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005			20240305192526.0
008			220802b |||||||| |||| 00| 0 eng d
020			_a 1447165365
020			_a 9781447165361
040			_cDLC
082			_a616.5 OZK
100			_a Esen Özkaya _941133
222			_aAcad Dermatol ACEIs acetazolamide Acute generalized exanthematous adverse cutaneous drug AGEP Allergy alopecia amiodarone amlodipine angioedema Angioedema/urticaria angiotensin II receptor antibodies ARBs Arch Dermatol aspirin associated beta-blockers bullous pemphigoid captopril cardiovascular drugs cause CCBs Clin Exp Dermatol clinical clopidogrel Contact Dermatitis corticosteroids cross-reactivity cutaneous adverse cutaneous drug reactions cutaneous reactions Dermatol Venereol diltiazem diuretics drug rash Drug-induced lupus erythematosus eczematous eruption edema enalapril eosinophilia and systemic erythema multiforme erythroderma exanthematous pustulosis Fixed drug eruption furosemide heparin hydrochlorothiazide hyperpigmentation hypersensitivity reactions induced lesions lichen planus Lichenoid drug eruption lichenoid eruption lisinopril LMWHs losartan maculopapular eruption methyldopa mexiletine mucosal necrosis nifedipine oral Özkaya patch test patch test reactions patients pemphigus phenytoin photopatch testing photosensitivity positive patch test propranolol Pruritus psoriasis purpura quinidine rash with eosinophilia receptor blockers rechallenge reported simvastatin statins Stevens-Johnson syndrome Stevens–Johnson subacute cutaneous lupus sulfonamide systemic symptoms therapy ticlopidine toxic epidermal necrolysis ulcers urticaria valsartan vasculitis verapamil
245			_aAdverse Cutaneous Drug Reactions to Cardiovascular Drugs
250			_a illustrated
260			_aDepartment of Dermatology Istanbul University Istanbul Medical Faculty Istanbul Turkey _b Springer _c2014
300			_a259 pages
520			_aAdverse cutaneous drug reactions (ACDR) are among the most frequent events in patients receiving drug therapy. Cardiovascular (CV) drugs are an important group of drugs with potential risk of developing ACDR especially in elderly as marketing of more new drugs and their prescription continue to increase. However, like with most other drugs the exact incidence of cutaneous side effects from CV drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable designation of a certain drug as the cause of a certain type of reaction can rarely be made. Apart from the well-known angioedema/urticaria from ACE inhibitors, lichen planus / lichenoid reaction from beta adrenergic blockers and photosensitivity from thiazid diuretics, ACDR from CV drugs might be seen in a wide spectrum extending to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis or drug hypersensitivity syndrome. In this comprehensive review, the reported types of ACDR to CV drugs will be discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis.
600			_xMedical / Dermatology _926960
600			_xMedical / Clinical Medicine _926816
600			_x Medical / Cardiology _926817
600			_x Medical › Dermatology _927797
700			_a Kurtuluş Didem Yazganoğlu _941134
942			_2ddc _cEB
999			_c8006 _d8006