000			03822nam a22003377a 4500
003			OSt
005			20240305192500.0
008			220616b |||||||| |||| 00| 0 eng d
020			_a3319022881
020			_a9783319022888
040			_cdlc
082			_a610.28
100			_aFilippo Rossi _939187
245			_aControlled Drug Delivery Systems _bTowards New Frontiers in Patient Care _cSpringerBriefs in Applied Sciences and Technology _h PoliMI SpringerBriefs
250			_a illustrated
260			_aDepartment of Chemistry, Materials and Chemical Engineering Politecnico di Milano Milan Italy _b Springer _c2016
300			_a 100 pages
505			_aContents: Chemical Engineering and Medicine A Mass Transport Matter Overview on Polymeric Drug Delivery Systems Functional Polymers for Drug Delivery Drug Eluting Stent
520			_aThis book offers a state-of-the-art overview of controlled drug delivery systems, covering the most important innovative applications. The principles of controlled drug release and the mechanisms involved in controlled release are clearly explained. The various existing polymeric drug delivery systems are reviewed, and new frontiers in material design are examined in detail, covering a wide range of polymer modification techniques. The concluding chapter is a case study focusing on use of a drug-eluting stent. The book is designed to provide the reader with a complete understanding of the mechanisms and design of controlled drug delivery systems, and to this end includes numerous step-by-step tutorials. It illustrates how chemical engineers can advance medical care by designing polymeric delivery systems that achieve either temporal or spatial control of drug delivery and thus ensure more effective therapy that eliminates the potential for both under- and overdosing. _bCommon terms and phrases; acid adinazolam agarose Anseth applications approach artery biocompatibility biodegradable biomaterials biomedical bonds bone cell chemical engineering chemistry considered constant controlled drug delivery Controlled Release copolymer cross-linked ð Þ D0 ¼ degradation depends Diels-Alder Diels-Alder reaction dienophile diffusion coefficient drug concentration drug delivery drug delivery systems drug release drug-eluting stent equation equilibrium extracellular Fatin-Rouge Fickian functional polymers groups hydrodynamic radius hydrogels hydrophilic implants increasing ion diffusion Journal kinetics ligands Macromolecules macromonomers materials matrix mechanical membrane Milano molecular weight molecules monomer Moreover nanoparticles parameters Peppas peptides Perale permeability physical Politecnico di Milano polymer chains polymer concentration Polymer Science polymeric post-polymerization modification proliferation properties protein release profile represent Reproduced with permission restenosis Rossi scaffolds self-diffusion coefficient Semi-dilute polymer solutions Shoichet small-sized diffusants solute diffusion solvent spinal cord injury strategies studied swelling swollen synthetic polymers temperature thiol thiol-ene reaction tissue engineering transport volume fraction
600			_xTechnology & Engineering / Materials Science / General _931306
600			_xTechnology & Engineering / Manufacturing _939188
600			_x Technology & Engineering / Industrial Engineering _939189
600			_x Technology & Engineering / Chemical & Biochemical _928700
600			_xTechnology & Engineering / Biomedical _927075
600			_x Science / Chemistry / Industrial & Technical _928328
600			_xMedical / General Medical / Pharmacy _939190
600			_xScience › Chemistry › Industrial & Technical _928329
700			_aGiuseppe Perale _939191
700			_a Maurizio Masi _939192
942			_2ddc _cEB
999			_c7284 _d7284