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020			_a0123860083
020			_a9780123860088
040			_cdlc
082			_a615.3
100			_aDonald R. Mattison _938587
110			_aElsevier Science _938588
245			_aClinical Pharmacology During Pregnancy
260			_aLondon _bAcademic Press _c2012
300			_a 488 pages
505			_aContents: 1 Introduction 2 Physiologic Changes During Pregnancy 3 Impact of Pregnancy on Maternal Pharmacokinetics of Medications 4 Medications and the Breastfeeding Mother 5 Fetal Drug Therapy an Evolving Therapeutic Concept 7 What is Sufficient Evidence to Justify a Multicenter Phase 3 Randomized Controlled Trial in Obstetrics? 8 Ethics of Clinical Pharmacology Research in Pregnancy 15 Substance Use Disorders 16 Diabetes in Pregnancy 17 Cardiovascular Medications in Pregnancy 18 Antidepressants in Pregnancy 19 Uterine Contraction Agents and Tocolytics 20 Antenatal Thyroid Disease and Pharmacotherapy in Pregnancy 21 Dermatological Medications and Local Therapeutics 22 Vitamins Minerals Trace Elements and Dietary Supplements 9 Pharmacogenomics in Pregnancy 10 Analgesics and AntiInflammatory General and Local Anesthetics and Muscle Relaxants 11 The Management of Asthma During Pregnancy 12 Updated Guidelines for the Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum 13 Clinical Pharmacology of AntiInfectives During Pregnancy 14 Chemotherapy in Pregnancy 23 Herbs and Alternative Remedies 24 Envenomations and Antivenoms During Pregnancy 25 Gastrointestinal Disorders Index _tClinical Pharmacology During Pregnancy
520			_aClinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are covered, as are research issues, including clinical trial design and ethical considerations. Uses an evidence-based approach for therapeutics during pregnancy Includes a summary of specific medications by indication with up-to-date information on dosing and efficacy in pregnancy for the given indication _bCommon terms and phrases: acid activity addiction administration adverse agents alcohol anesthesia anesthetic antidepressants antivenom associated asthma atenolol birth weight breast cancer breast milk breastfeeding buprenorphine calcium changes clearance Clin Pharmacol clinical clonidine concentrations congenital corticosteroids cross the placenta decreased delivery depression digoxin disease disorders dose drug efficacy envenomation enzymes excreted exposure FDA category fetal fetus gestational diabetes glucose glyburide Gynecol half-life hemodynamic hepatic human hypertension hypothyroidism increased risk indomethacin infants infections inhibitors insulin intravenous lactation malformations maternal medications Metab metabolism metformin methadone mother nancy neonatal nifedipine non-pregnant ObstetGynecol Obstetrics opioid oral outcomes perinatal pharmacodynamic pharmacokinetics pharmacological placenta plasma postpartum potential preeclampsia preg pregnancy category pregnant patients pregnant women prenatal preterm labor protein binding receptor recommended renal reported result safety serum side effects symptoms syndrome teratogenic therapeutic therapy third trimester thyroid tion tocolysis tocolytic toxicity treat treatment trials trimester trimester of pregnancy urine uterine vitamin weeks
600			_xMedical / Pharmacology _927230
600			_xMedical / Gynecology & Obstetrics _926832
600			_x Medical › Pharmacology _927231
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999			_c7009 _d7009