000			03449nam a22002777a 4500
003			OSt
005			20240305192437.0
008			220530b |||||||| |||| 00| 0 eng d
020			_a3319092685
020			_a9783319092683
040			_cdlc
100			_aElena Aikawa _938183
245			_aCardiovascular Imaging _b Arterial and Aortic Valve Inflammation and Calcification
250			_a illustrated
260			_aCardiovascular Medicine Brigham and Women’s Hospital Harvard Medical School Boston , MA USA _b Springer _c2014
300			_a 389 pages
505			_aContents: Imaging Insights into Mechanisms of Calcific Aortic Valve Disease CAVD and Calcification Clinical Imaging of Cardiovascular Inflammation and Calcification Index
520			_aThis book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses. _bCommon terms and phrases: activity adhesion molecules Aikawa angiography antibodies aorta aortic stenosis aortic valve arterial inflammation arterial wall Arterioscler Thromb Vasc assessment associated atherosclerotic lesions atherosclerotic plaques blood calcification calcium cardiac cathepsin CAVD cholesterol Circ Circulation clinical collagen contrast agent correlated demonstrated dendrimers detection diabetes echocardiography endothelial cells evaluation Fayad FDG uptake FDG-PET/CT imaging fibrous cap fluorescence high-risk human increased inflammation inflammatory injection iron oxide ischemia IVUS JACC Cardiovasc Imaging Jaffer JAm Coll Cardiol left ventricular leukocytes Libby lipid lipoprotein macrophages magnetic resonance imaging marker matrix metabolic mice micelles microbubbles molecular imaging myocardial infarction nanoparticles necrotic core NIRF imaging noninvasive Nucl optical OSE-targeted P-selectin patients peptide PET/CT pioglitazone plaque inflammation plaque rupture platelet positron emission tomography preclinical probes protease protein risk signal statins stent studies Tahara targeted techniques therapy Thromb Vasc Biol thrombus tion tissue Tsimikas ultrasound valvular vessel visualize vulnerable plaque Weissleder
600			_xMedical / Radiology, Radiotherapy & Nuclear Medicine _926866
600			_x Medical / Clinical Medicine _926816
600			_xMedical / Cardiology _926817
600			_xMedical / Biochemistry _926818
600			_xMedical / Allied Health Services / Imaging Technologies _926763
600			_xMedical › Allied Health Services › Imaging Technologies _926754
942			_2ddc _cEB
999			_c6737 _d6737