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| 008 | 170803s2017 gw |||| o |||| 0|eng | ||
| 010 | _a 2019757969 | ||
| 020 | _a9783319581064 | ||
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_a10.1007/978-3-319-58106-4 _2doi |
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| 035 | _a(DE-He213)978-3-319-58106-4 | ||
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_aDLC _beng _epn _erda _cDLC |
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_a571.84 _223 |
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_aMolecules, Systems and Signaling in Liver Injury / _cedited by Wen-Xing Ding, Xiao-Ming Yin. |
| 250 | _a1st ed. 2017. | ||
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2017. |
|
| 300 | _a1 online resource (XV, 290 pages 25 illustrations, 20 illustrations in color.) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 490 | 1 |
_aCell Death in Biology and Diseases, _x2625-2902 |
|
| 520 | _aThis essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury. The book starts with a discussion of lipotoxicity in non-parenchymal cells, followed by a discussion of cell death and autophagy in cholangiocytes, hepatic stellate cells and Kupffer cells in hepatic biliary diseases, fibrosis and liver inflammation. The book also covers Bcl-2 family proteins, beta-catenin and HMGB1 signaling in regulating cell death in the liver as well as mitochondria, ER stress and gut microbiota on liver injury. The Cell Death in Biology and Diseases series has recruited world experts ranging from basic scientists to clinicians on cell death in liver diseases. Likewise the contributors of this volume are leaders in their fields with worldwide expertise and perspective. Molecules, Systems and Signaling in Liver Injury is an essential companion to Hepatocytes and Non-Parenchymal Cells and Diseases. It is beneficial for both clinicians and basic scientists and is relevant to those working on drug discovery for preventing and treating liver diseases by targeting cell death and autophagy pathways. | ||
| 588 | _aDescription based on publisher-supplied MARC data. | ||
| 650 | 0 |
_aApoptosis. _928076 |
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_aCell cycle. _92147 |
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_aCell physiology. _928078 |
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_aHepatology. _96481 |
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_aCell Cycle Analysis. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16030 _92148 |
| 650 | 2 | 4 |
_aApoptosis. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16060 _928076 |
| 650 | 2 | 4 |
_aCell Physiology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L33010 _928079 |
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_aHepatology. _0https://scigraph.springernature.com/ontologies/product-market-codes/H33088 _96481 |
| 650 | 2 | 4 |
_aMembrane Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16050 _928080 |
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_aDing, Wen-Xing. _eeditor. _928081 |
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| 700 | 1 |
_aYin, Xiao-Ming. _eeditor. _928082 |
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_iPrint version: _tMolecules, systems and signaling in liver injury _z9783319581057 _w(DLC) 2017945288 |
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_iPrinted edition: _z9783319581057 |
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_iPrinted edition: _z9783319581071 |
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_iPrinted edition: _z9783319863221 |
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_aCell Death in Biology and Diseases, _x2625-2902 _928083 |
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