000			03425nam a22003377a 4500
001			20250705152013.0
003			20250705152013.0
005			20250707121926.0
008			250705b |||||||| |||| 00| 0 eng d
028			_bWurzburg Road 35, Premises, Post Code: 33102 |
028			_b P. O. Box 1464 Mwanza, Tanzania |
028			_bPhone: (255) 28-298-3384 |
028			_bFax: (255) 28-298-3386 |
028			_bEmail: vc@bugando.ac.tz |
028			_bWebsite: www.bugando.ac.tz.
040			_cddc
041			_aEnglish
100			_aMinde Mercy Maria _dSAUT/BUCHS/MMED/4379/T/06
245			_aPrevalence of Congenital Malaria and Associated Factors among Newborns in Mwanza, Tanzania.
260			_a Mwanza, Tanzania | _bCatholic University of Health and Allied Sciences [CUHAS-Bugando] | _c2009
300			_ax; 46 Pages
300			_aIncludes References
520			_aAbstract: Background: Congenital malaria has generally been considered rare in areas where malaria is endemic, however it is increasingly being reported among babies born to mothers residing in endemic areas. Given the high morbidity and mortality associated with malaria it is important to determine the current situation in the lake zone. This study was designed to determine the prevalence of congenital malaria and associated factors among newborns delivered at Bugando Medical Centre in Mwanza, Tanzania. Materials and methods: A cross-sectional study was conducted on 383 mothers who delivered at Bugando Medical Centre between July and September 2008. Serial sampling was used to obtain the sample size. The Sociodemographic and clinical characteristic of mothers were documented. Samples of maternal, placental, cord and neonatal blood were taken and stained with Giemsa and examined for malaria parasites. Results: The prevalence of congenital malaria was 14/383 ana parasite counts were generally low ranging from 4-10 parasites/200 WBCs. Positive parasitemia was found in 24 (6.2%) of mother’s peripheral blood smears, 6 (1.6%) and 2 (0.5%) of the placental and cord blood smears, respectively. Plasmodium falciparum was the only species identified. In the multivariate regression model, factors the remained independently associated with congenital malaria were positive maternal parasitemia (OR 5.65, {95%CI 1.40 – 22.77}, P=0.02) and mothers’ level of education; secondary/higher Learning (OR 3.5, {95%CI 1.16; 10.52}, P=0.03). Conclusion: Congenital malaria is not uncommon as previously thought. Maternal parasitemia during delivery and maternal level of education (secondary or higher) were found to be associated with congenital malaria. Recommendation: Malaria should also be considered in the work up for neonatal sepsis. Pregnant women who present with fever during ANC/delivery should be screened and treated for malaria, and neonates born to parasitemic mother should be screened for malaria and if infected followed up for development of symptoms or spontaneous clearance of parasites. A large multicenter study should be done to evaluate other factors which may be associated with congenital malaria.
600			_xEpidemiology, Biostatistics and Behavioral Sciences
600			_xPaediatrics and Child Health
600			_xInternal Medicine
700			_dSafari Kinung'hi
700			_dJohanes B Kataraihya
700			_dChristian Schmidt
942			_cMP _n0
999			_c29858 _d29858