000			02186nam a22002657a 4500
001			20241105171040.0
003			OCoLC
005			20241105171442.0
008			241105b |||||||| |||| 00| 0 eng d
010			_a 2016936684
020			_a 978-3-319-28036-3
020			_a978-3-319-28038-7 (eBook)
040			_cddc
041			_aEnglish
100			_qLaurie E. Cohen
240			_aGrowth Hormone Deficiency.
245			_aGrowth Hormone Deficiency _b Physiology and Clinical Management.
260			_aBoston Children’s Hospital Harvard Medical School Boston , MA , USA | _bSpringer International Publishing Switzerland | _c 2016.
300			_a232 Pages
300			_aIncludes References and Index
520			_aProviding the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.
600			_xDiseases, Endocrinology, Medical / Clinical Medicine, Medical / Endocrinology & Metabolism, Medical / Diseases, Science / Life Sciences / Biochemistry, Dwarfism, Pituitary, Dwarfism, Pituitary -- Treatment, Medicine, Medicine and Public Health, Metabolism -- Disorders.
856			_u DOI 10.1007/978-3-319-28038-7
942			_2ddc _cEB _n0
999			_c29660 _d29660