000 03377nam a22002897a 4500
001 20241102135253.0
003 OCoLC
005 20241102135759.0
008 241102b |||||||| |||| 00| 0 eng d
010 _a2018957321
020 _a 978-3-319-96988-6
020 _a978-3-319-96989-3 (eBook)
040 _cddc
041 _aEnglish
100 _qGabriel G. Malouf
222 _aadults anaplasia associated bevacizumab bilateral ccRCC CDC patients cell RCC cell renal cell characterized chemotherapy Children's Oncology Group ChRCC chromophobe chromophobe renal cell chromosome clear cell renal clear-cell Clin Oncol COG collecting duct collecting duct carcinoma cytogenetic diagnosis differentiation doxorubicin epithelial everolimus fusion transcripts gemcitabine gene genetic genomic germline mutations grade histologic histologic subtype HLRCC HPRC imaging immunohistochemical kidney cancer lesions lung lymph node malignancies Malouf median metastasectomy metastatic metastatic disease molecular non-clear cell outcome papillary RCC papillary renal cell Pathology pathway patients with metastatic Pediatr phase pRCC prognostic factors RCC renal carcinoma renal cell carcinoma renal masses renal medullary carcinoma renal tumors reported resection risk RMC sarcomatoid component sarcomatoid renal cell sickle cell SIOP SMARCB1 sorafenib sporadic sRCC stage sunitinib Surg Pathol surgery surgical syndrome Tannir targeted therapy TFE3 TFEB translocation renal cell tRCC treatment tumor suppressor Urol VHL Wilms tumor WT XRT
240 _aRare Kidney Tumors
245 _a Rare Kidney Tumors
_bComprehensive Multidisciplinary Management and Emerging Therapies.
260 _aDepartment of Hematology and Oncology Strasbourg University Hospital Hopital Civil Strasbourg France |
_bSpringer Nature Switzerland AG |
_c 2019.
300 _a131 Pages
300 _aIncludes References
520 _aThis book provides clinicians with clear guidance on treatment decision-making in patients with rare kidney cancers. After a brief review on epidemiology, pathology, and biology, each chapter focuses on the multidisciplinary management of a particular tumor subtype using the full range of available cancer therapy modalities, including surgery, radiotherapy, chemotherapy, targeted therapies, and immunotherapy. Emerging therapies and future directions in the management of each cancer subtype are also discussed. The chapters are all written by multidisciplinary teams of international experts comprising at least a urologist, a medical oncologist, and a pathologist. Rare kidney cancers represent 15% of renal cell carcinomas. In comparison with clear cell renal cell carcinomas, little is known about the biology of such cancers, and few trials have reported on the efficacy of targeted therapies in the metastatic setting. Optimal management thus poses significant challenges and often requires a multidisciplinary team. This book will be an ideal reference guide for all clinicians involved in the care of patients with these orphan tumors.
600 _x Medical / Clinical Medicine, Medical / Oncology / General, Medical / Pediatrics, Medical / Urology, Oncology, Pediatrics, Urology, Kidneys -- Cancer -- Diseases, Medicine.
700 _qNizar M. Tannir
856 _uhttps://doi.org/10.1007/978-3-319-96989-3
942 _2ddc
_cEB
_n0
999 _c29570
_d29570