000			03550nam a22002657a 4500
001			20241102100521.0
003			OCoLC
005			20241102100942.0
008			241102b |||||||| |||| 00| 0 eng d
020			_a978-3-031-65807-5
020			_a978-3-031-65808-2 (eBook)
022			_a2731-4561
022			_a2731-457X (electronic)
040			_cddc
041			_aEnglish
100			_qNima Rezaei
222			_aactivity adjuvant angiogenesis antibody anticancer antigen antitumor apoptosis associated BC biomarkers BRCA1 breast cancer cells breast cancer treatment breast tumor cancer therapy CAR-T cell carcinoma CD8+ cellular chemokine chemotherapy Chen cisplatin Clin clinical trials co-delivery combination cytokines cytotoxic delivery disease DNA docetaxel doxorubicin drug resistance effects efficacy enhanced estrogen evaluation everolimus expression fulvestrant G gene genetic genomic H HER2 HER2-positive HER2+ hormone Huang immune response immune system Immunol immunosuppressive immunotherapy induce infiltration inhibition invasion kinase lapatinib Liu lymphocytes macrophages mechanisms metastasis metastatic metastatic breast cancer microRNA miRNAs Mol molecular molecules mutations nanoparticles negative breast cancer neoadjuvant neutrophils Oncol oncolytic virotherapy oncolytic viruses outcomes overexpression paclitaxel pembrolizumab phase potential precision medicine prognostic proliferation promote protein risk RNA role Sci siRNA strategies stromal TILS subtypes suppressor survival T-cell tamoxifen therapeutic tissues TME TNBC trastuzumab triple-negative breast cancer tumor cells tumor microenvironment tumor-infiltrating vaccines virotherapy virus Wang Xu Zhang
245			_aBreast Cancer Genetics, Immunology, and Immunotherapy _bAn Interdisciplinary Approach.
260			_aDepartment of Clinical Immunology Karolinska Institutet Stockholm, Sweden | _b Springer Nature Switzerland AG | _c2024
490			_a Interdisciplinary Cancer Research
520			_aZusammenfassung: Genetics have a role in the presence of breast cancer, while the potential role of the immune system leads to consideration of immunotherapy in the treatment of the disease, particularly in metastatic triple-negative breast cancer. The sixth volume of the "Interdisciplinary Cancer Research" series, entitled "Breast Cancer Genetics, Immunology, and Immunotherapy: An Interdisciplinary Approach" publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer. This interdisciplinary series is of special value to researchers working on immunology, genetics, and practitioners working on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value to researchers, oncologists, geneticists, and immunologists who wish to extend their knowledge on breast cancer
600			_xBreast -- Cancer -- Genetic aspects -- Immunological aspects.
856			_u https://doi.org/10.1007/978-3-031-65808-2
942			_2ddc _cEB _n0
999			_c29550 _d29550