000			01871nam a22002657a 4500
001			20241028155346.0
003			OCoLC
005			20241028155816.0
008			241028b |||||||| |||| 00| 0 eng d
010			_a2016933678
020			_a 978-3-319-06712-4
020			_a978-3-319-06713-1 (eBook)
040			_cddc
041			_aEnglish
100			_qFernando Ferreira Costa
245			_a Sickle Cell Anemia _bFrom Basic Science to Clinical Practice.
260			_aLondon | _bSpringer International Publishing Switzerland | _c 2016.
300			_a439 Pages
300			_aIncludes references
520			_aAlthough sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.
600			_xClinical biochemistry, Hematology, Internal medicine, Medical / Biochemistry, Medical / Clinical Medicine, Medical / General, Medical / Hematology, Medical / Internal Medicine, Medical sciences, Science / Life Sciences / Biochemistry, Medical / Research, Medicine, Medicine and Public Health, Sickle cell anemia.
700			_q Nicola Conran
856			_uDOI 10.1007/978-3-319-06713-1
942			_2ddc _cEB _n0
999			_c29374 _d29374