000 02255nam a22002657a 4500
001 20241023111613.0
003 OCoLC
005 20241023112057.0
008 241023b |||||||| |||| 00| 0 eng d
020 _a 978-3-030-38691-7
020 _a 978-3-030-38692-4 (eBook)
040 _cddc
041 _aEnglish
082 _a616.994 WON
100 _qJeffrey Y. C. Wong
245 _aTotal Marrow Irradiation
_bA Comprehensive Review
260 _aDepartment of Radiation Oncology City Of Hope National Medical Center Duarte, CA USA |
_bSpringer Nature Switzerland AG |
_c 2020.
300 _a193 Pages
300 _aIncludes References
520 _aThis book, written by a team of international experts, concisely reviews the rationale and clinical application of image-guided total marrow irradiation, a rapidly emerging area in radiation oncology and hematopoietic cell transplantation. The aim is to provide the practicing radiation oncologist, hematologist, medical physicist, and bone marrow transplant researcher with a fundamental understanding of key aspects and an appreciation of the increasing significance of total marrow irradiation as conditioning for bone marrow transplantation. Detailed attention is paid to the impacts of recent advances in radiation therapy technology, functional PET and MRI, and understanding of the response of bone marrow to radiation. Full consideration is also given to the ways in which technological advances in image-guided radiation therapy have created new opportunities to treat bone marrow transplant patients with limited transplant options due to advanced disease, age, or co-morbidities. Further topics covered include the ways in which cancer stem cells and the marrow microenvironment influence response to radiation therapy and the implementation of new-generation predictive radiobiologic factors in the clinic.
600 _xHematology, Medical / Clinical Medicine, Medical / Hematology, Medical / Oncology / General, Medical / Radiology, Radiotherapy & Nuclear Medicine, Oncology, Radiology, Bone marrow -- Radiotherapy, Bone marrow purging, Radiotherapy.
700 _qSusanta K. Hui
856 _u https://doi.org/10.1007/978-3-030-38692-4
942 _2ddc
_cEB
_n0
999 _c29301
_d29301