000			03001nam a22002777a 4500
001			20241023104657.0
003			OCoLC
005			20241023105041.0
008			241023b |||||||| |||| 00| 0 eng d
020			_a 978-3-030-16883-4
020			_a 978-3-030-16884-1 (eBook)
040			_cddc
041			_aEnglish
082			_a616.994 2 CER
100			_qGiovanni Luca Ceresoli
245			_a Mesothelioma _bFrom Research to Clinical Practice.
260			_aDepartment of Medical Oncology Humanitas Gavazzeni Hospital Bergamo Italy | _bSpringer Nature Switzerland AG | _c 2019
300			_a341 Pages
300			_aIncludes References
520			_a This book offers an updated review of malignant mesothelioma, including the latest advances in our understanding of its genetic control and molecular biology, as well as pre-clinical and clinical research. It also presents state-of-the-art diagnostic approaches and therapeutic options, and an open discussion on the future prospects for patient management. Malignant mesothelioma is an enormous global health problem related to asbestos exposure. Despite the best efforts of scientists and oncologists, the prognosis for those affected remains poor. Due to anatomical characteristics and non-specific symptoms, the diagnosis of mesothelioma at an early stage is often difficult, while surgery and radiotherapy are only of limited use, even if some multimodality approaches seem promising. In turn, medical treatments are sometimes successful in tumor control, but have little impact on overall survival. However, advances in our understanding of the disease’s biology, together with the availability of new drugs and combinations, make mesothelioma an essential and highly topical field for pre-clinical and clinical studies. This book is subdivided into four parts: epidemiology and preclinical data, diagnosis, therapy, and extrathoracic mesothelioma. It highlights the progress made in a variety of areas – e.g. in vitro and in vivo experimental models, genetics, environment, biomarkers, targeting agents, immunotherapy, metabolic imaging and ongoing clinical trials – and describes the standard clinical management of mesothelioma patients, including those with extra-thoracic localizations. Given its scope, the book offers an invaluable tool for researchers, oncologists and clinicians alike.
600			_xBioinformatics, Biology—Research, Immunology, Medical / Clinical Medicine, Medical / Genetics, Medical / Immunology, Medical / Oncology / General, Medical / Radiology, Radiotherapy & Nuclear Medicine, Medical / Research, Medical genetics, Medicine—Research, Nuclear medicine, Oncology, Science / Life Sciences / Anatomy & Physiology, Science / Life Sciences / Molecular Biology, Computational biology, Human genetics, Medicine, Mesothelioma.
700			_qEmilio Bombardieri
700			_q Maurizio D’Incalci
856			_u https://doi.org/10.1007/978-3-030-16884-1
942			_2ddc _cEB _n0
999			_c29298 _d29298