000 03209nam a22003617a 4500
001 20240923131814.0
003 20240923131814.0
005 20240923132610.0
008 240923b |||||||| |||| 00| 0 eng d
028 _b Wurzburg Road 35, Premises, Post Code: 33102 |
028 _b P. O. Box 1464 Mwanza, Tanzania |
028 _b Phone: (255) 28-298-3384 |
028 _b Fax: (255) 28-298-3386 |
028 _b Email: vc@bugando.ac.tz |
028 _b Website: www.bugando.ac.tz
040 _cddc
041 _aEnglish
041 _aKiswahili
100 _eCUHAS/BM/1001229/T/21
_q Hassani Rajabu Hassan
245 _aSeroprevalance Of Hepatitis E Virus Infection among Pregnant Women Attending Healthcare Centers in Mwanza, Tanzania.
260 _aMwanza, Tanzania |
_b Catholic University of Health and Allied Sciences [CUHAS-Bugando] |
_c2024.
300 _a47 Pages
300 _aIncludes References
520 _aAbstract: Introduction: Hepatitis E virus (HEV) is one of the important pathogens of public health importance, documented as the most common cause of viral hepatitis in developing countries. HEV has been noted to cause spontaneous abortion, premature delivery, maternal and infant mortality in pregnancy in areas where HEV has been noted. There is no routine vaccination program to vaccinate actively sexual women of child baring age thus making them at great risk of transmitting HEV infection to fetus during pregnancy. Thus, this study aims to determine the prevalence and factors associated with HEV infections among pregnant women attending antenatal clinics in Mwanza, Tanzania as to provide the baseline serological evidence of Hepatitis E among pregnant women attending antenatal clinics. Methodology: A hospital based cross-sectional study involving 200 pregnant women in Mwanza, Tanzania was to be conducted between May to August 2024. Serum samples from pregnant women were tested for HEV antibodies, IgG and IgM, using qualitative immunochromatographic tests. Data entered into the Microsoft excel sheet for clearing and coding then analyzed by using Stata version 15. Results: The median age [interquartile range; IQR] of the study participants in years was 27[18-42]. The prevalence of HEV antibodies among 200 pregnant women was found to be 0.0%. The factors associated with HEV positivity were not analyzed. Conclusion: Considering the complications of chronic HEV infections, preventive strategies and appropriate precautions to pregnant women are highly recommended. Also, further and more studies on HEV with large sample size and more specific and sensitive methods in different parts of the country are highly recommended, to monitor the trend of the disease burden.
600 _x Microbiology & Immunology
600 _xObstetrics & Gynaecology
600 _xMicrobiology & Immunology
700 _qMariam Mwinjuma Mirambo
700 _qFridolin Felix Mujuni
700 _qHelmut Adrian Nyawale
856 _zResearch Report Submitted in Partial Fulfillment for The Award of Bachelor of Medical Laboratory Sciences Degree of Catholic University of Health and Allied Sciences.
942 _2ddc
_cCR
_n0
999 _c28845
_d28845