000			02728nam a22003617a 4500
001			20240903104914.0
003			20240903104914.0
005			20240926130656.0
008			240903b |||||||| |||| 00| 0 eng d
028			_bWurzburg Road 35, Premises, Post Code: 33102 |
028			_b P. O. Box 1464 Mwanza, Tanzania |
028			_b Phone: (255) 28-298-3384 |
028			_b Fax: (255) 28-298-3386 |
028			_bEmail: vc@bugando.ac.tz |
028			_b Website: www.bugando.ac.tz.
040			_cddc
041			_aEnglish
041			_aKiswahili
100			_e CUHAS/MD/4003977/T/19 _qEvance R Philbert
245			_aClinical Presentations, Risk Factors and Outcomes of Cryptococcal Meningitis Among Patients Diagnosed with HIV/AIDS, Attending Clinic at Bugando Medical Centre, Mwanza, Tanzania.
260			_aMwanza, Tanzania | _bCatholic University of Health and Allied Sciences [CUHAS-Bugando] | _c2024.
300			_a35 Pages
300			_aIncludes References
520			_aAbstract: Background: Cryptococcal meningitis is the most common lethal fungal infection in patients with HIV/AIDS worldwide. It accounts for more than 22% of HIV/AIDS-related mortality in Africa. Therefore, screening and early anti-fungal treatment are important for reducing deaths caused by Cryptococcal meningitis. We conducted research to provide updated information regarding Cryptococcal meningitis following initiation of prophylactic medications. Method: A retrospective cross-sectional hospital-based study was done among newly diagnosed patients with HIV/AIDS aged >18 years who attend clinic at BMC. Sociodemographic and clinical information were collected using a structured checklist Results: Among 141 patients who were diagnosed with HIV/AIDS only 4(2.84%) were diagnosed with CM. All patients diagnosed with CM were female, had CD4 cell count of <200cells/mm3 and had poor adherence to ART. Conclusion: This study reports low prevalence of CM among patients diagnosed with HIV/AIDS at BMC but there is high CM associated mortality, even with use of Amphotericin B based therapy, fluconazole and Flucytosine. Therefore, there is a need of evaluating and reviewing the treatment guidelines used at our clinical setting to help reduce the mortality.
600			_xCommunity Medicine
600			_xInternal Medicine
600			_xMicrobiology & Immunology
700			_q Basinda Namanya Samson
700			_qElizabeth John
700			_qHelmut Adrian Nyawale
856			_zResearch Report Submitted for Partial Fulfillment of The Requirements for The Award of Bachelor of Doctor of Medicine at The Catholic University of Health and Allied Sciences.
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999			_c28602 _d28602