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020 _a978-3-540-75862-4
020 _a978-3-540-75863-1
022 _a0942-5373
022 _a2197-4187 (electronic) 4
040 _cddc
041 _aEnglish
100 _qPhilip Rubin
245 _aALERT – Adverse Late Effects of Cancer Treatment
_bNormal Tissue Specific Sites and Systems
260 _aLondon :
_bSpringer-Verlag Berlin Heidelberg :
_c2014
300 _a710 Page
300 _aIncludes References
490 _aNormal Tissue Specific Sites and Systems
_vVolume 2
520 _aThe literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT – Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
600 _xMedical / Allied Health Services / Imaging Technologies, Medical / Biochemistry, Medical / Clinical Medicine, Medical / Diagnostic Imaging / General, Medical / Oncology / General, Medical / Radiology, Radiotherapy & Nuclear Medicine, Oncology, Radiology, Radiology, Medical, Cancer -- Treatment -- Alternative treatment, Cancer -- Treatment -- Complications, Medical radiology, Medicine, Radiotherapy
700 _qLouis S. Constine
700 _qLawrence B. Marks
856 _uDOI 10.1007/978-3-540-75863-1
942 _2ddc
_cEB
_n0
999 _c28448
_d28448