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008			240612b |||||||| |||| 00| 0 eng d
040			_cddc
041			_aEnglish
100			_qNeema Kayange
245			_aSeroprevalence of Dengue and Chikungunya Virus Infections in Children Living in Sub-Saharan Africa _bSystematic Review and Meta-Analysis
260			_aMwanza, Tanzania : _bCatholic University of Health and Allied Sciences [CUHAS-Bugando] : _c2023
300			_aPages 01-18
300			_aIncludes References
490			_vChildren (Basel) . 2023 Oct 7;10(10):1662. doi: 10.3390/children10101662.
520			_aAbstract : Dengue and chikungunya viruses are frequent causes of malarial-like febrile illness in children. The rapid increase in virus transmission by mosquitoes is a global health concern. This is the first systematic review and meta-analysis of the childhood prevalence of dengue and chikungunya in Sub-Saharan Africa (SSA). A comprehensive search of the MEDLINE (Ovid), Embase (Ovid), and Cochrane Library (Wiley) databases was conducted on 28 June 2019, and updated on 12 February 2022. The search strategy was designed to retrieve all articles pertaining to arboviruses in SSA children using both controlled vocabulary and keywords. The pooled (weighted) proportion of dengue and chikungunya was estimated using a random effect model. The overall pooled prevalence of dengue and chikungunya in SSA children was estimated to be 16% and 7%, respectively. Prevalence was slightly lower during the period 2010-2020 compared to 2000-2009. The study design varied depending on the healthcare facility reporting the disease outbreak. Importantly, laboratory methods used to detect arbovirus infections differed. The present review documents the prevalence of dengue and chikungunya in pediatric patients throughout SSA. The results provide unprecedented insight into the transmission of dengue and chikungunya viruses among these children and highlight the need for enhanced surveillance and controlled methodology.
600			_x Sub-Saharan Africa
600			_xChikungunya virus
600			_x Dengue virus
600			_xPrevalence
600			_xSystematic review.
700			_qDuncan K Hau
700			_qKevin Pain
700			_qStephen E Mshana
700			_q Robert Peck
700			_qStephan Gehring
700			_q Britta Groendahl
700			_qPhilip Koliopoulos
700			_q Baraka Revocatus
700			_q Evarist B Msaki
700			_qOmbeva Malande
856			_uhttps://doi.org/10.3390/children10101662 _yhttps://doi.org/10.3390/children10101662
942			_2ddc _cVM _n0
999			_c28088 _d28088