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040 _cddc
041 _aEnglish
100 _qChuru Mwanaidi
245 _a Factors associated with adherence to oral HIV pre-exposure prophylaxis among female sex workers in the Mara Region, Tanzania: A 2022 cross-sectional study
260 _aMwanza, Tanzania :
_bCatholic University of Health and Allied Sciences [CUHAS – Bugando] :
_c2023
300 _aIncludes References
490 _aMedicine 102(36):p e34824, September 08, 2023.
520 _aAbstract : Female sex workers (FSWs) have a higher risk of acquiring human immunodeficiency virus (HIV) infection compared with the general female population. Tanzania adopted pre-exposure prophylaxis (PrEP) use for HIV-negative key populations in 2019 as a strategy to reduce HIV transmission. We aimed to identify factors associated with PrEP adherence among FSWs in Tanzania. We conducted a cross-sectional study of FSWs using oral HIV PrEP from June-July 2022 in 5 Mara Region districts. Stata software was used to analyze the quantitative data. Poor overall PrEP adherence was observed among FSWs, with adherence of 48.3% (174/360) and 43.3% (156/360) according to pill count and self-reports, respectively. Participants living with family members had 2.32 higher odds of PrEP adherence (adjusted odds ratio [aOR] = 2.32, 95% confidence interval [CI] = 1.27–42.23, P = .006) versus participants living alone or with friends. Moreover, FSWs who preferred pill packages had 1.41 higher odds of adherence (aOR = 2.43, [95% CI = 1.41–4.19, P = .001]); participants with a good perception of PrEP had 1.71 higher odds (aOR = 1.71, [95% CI = 1.01–2.91, P = .047]) of PrEP adherence. We found that living with family, pill packaging, and PrEP perception played significant roles in PrEP adherence among FSWs. Interventions to improve pill packaging, social support, and the perception of PrEP among FSWs should be intensified to increase adherence in this vulnerable population.
600 _xadherence, female sex workers, human immunodeficiency virus, pre-exposure prophylaxis
700 _qKulemba Khamis
700 _qKapesa Anthony
700 _qKajura Alphaxard
700 _qWilfred Diana
700 _e
_qBasinda Namanya
700 _qKaluvya Samwel
700 _qMageda Kihulya Pastory
856 _u http://dx.doi.org/10.1097/MD.0000000000034824
_y http://dx.doi.org/10.1097/MD.0000000000034824
942 _2ddc
_cVM
_n0
999 _c27944
_d27944