000			03355nam a22003257a 4500
001			CUHAS/BM/1000955T/20
003			CUHAS/BM/1000955T/20
005			20240305194013.0
008			231115b |||||||| |||| 00| 0 eng d
028			_bWurzburg Road 35, BMC Premises, Post Code: 33102 :
028			_b P. O. Box 1464, Mwanza – Tanzania :
028			_bPhone: +255 28 298 3384 :
028			_b Fax: +255 28 298 3386 :
028			_bEmail: vc@bugando.ac.tz :
028			_bwww.bugando.ac.tz
040			_bEnglish _cDDC
041			_aEnglish
041			_aKiswahili
100			_a Regan Yotham Gervas _d CUHAS/BM/1000955T/20
245			_aSero Prevalence of Brucella Melitensis Antibodies among Pregnant Women Attending Ante Natal Clinics in Unguja Zanzibar
260			_aMwanza, Tanzania: _bCatholic University of Health and Allied Sciences [CUHAS – Bugando] : _c©2023
300			_a44 Pages
300			_aIncludes References and Appendicies
520			_aAbstract: Background:Brucellosis is a serious public health issue that causes significant morbidity in both humans and animals. Pregnant women who have the Brucella melitensis infection run the risk of having unfavourable pregnancies, including miscarriage, stillbirth, premature labour, and low birth weight, among many other complications. Despite being widespread in tropical areas, there is little information on how prevalent it is among pregnant women, which means that there is little public awareness of the disease's possible risk factors, which makes control efforts more difficult. This research reveals the level of Brucella melitensis antibodies and its associated factors among pregnant women in Unguja, Zanzibar. Methods:This was a cross sectional study involving 270pregnant women attending antenatal clinics in Unguja Zanzibar between June and July 2023. Data was collected using a structured questionnaire. Venous blood sample was collected and serum was used for detection of Brucella melitensis antibodies by slide agglutination test as per manufacturer’s instructions(EUROCELL,UK). Data was analysed by STATA version 15. Result;A total number 270 pregnant women were enrolled in the study. The mean age of study participants was 26.9 years (±5.7), majority of them were married 245/270(90.7%) and most of them were from urban 236/270(87.41%).The seroprevalence of Brucella melitensis antibody was 4.4%.Brucella melitensis infection had a statistically significance associated with history of fever, myalgia and participant involved in animal keeping (OR 12.74[95%CI 2.59-6.76] p-value 0.002 ), (OR 8.34[95%CI 1.39-9.13] p-value 0.020), 0.000(OR 30.16[95%CI 4.97-65.6] p-value 0.000). Conclusion; Brucella melitensis antibody are prevalent among pregnant women in Unguja Zanzibar (4.4%), this is asign of exposure to Brucella pathogen.The identified main risk factor on pregnant women to this study it showed that those who have animal at home have greater chance to get Blucella melitensis infection. Also it showed that seroprevalence of Brucella melitensis antibody is significantly higher among those who have history of fever than myalgia.
600			_vMedical Laboratory Sciences
600			_xMicrobiology & Immunology
700			_a Mariam M. Mirambo
700			_a Helmut Nyawale
942			_2ddc _cCR
999			_c23137 _d23137