000			03019nam a22003137a 4500
001			CUHAS/BM/1001055/T/20
003			CUHAS/BM/1001055/T/20
005			20240305194006.0
008			231030b |||||||| |||| 00| 0 eng d
028			_bPhone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_bWebsite: www.bugando.ac.tz
035			_aCUHAS/BM/1001055/T/20
040			_cDDC
041			_aEnglish
041			_aKiswahili
100			_aAnodi Denis Mhoza _dCUHAS/BM/1001055/T/20
245			_aPrevalence of Hepatitis B Surface Antigens and Associated Factors among Pregnant Women Attending To Antenatal Care Clinics in Unguja, Zanzibar
260			_aMwanza, Tanzania: _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] : _c ©2023
300			_a57 Pages
300			_aIncludes References and Appendicies
520			_aAbstract: Introduction: Hepatitis B virus (HBV) infection is an infection of the liver that accounts for up to 80% of all cases of hepatocellular carcinoma worldwide. As of 2019, there were 354 million people worldwide infected with hepatitis B, of which 257 million were chronically infected. In Tanzania the prevalence ranges from 0.4%-11.8%. However, previous there was limited data on the magnitude of HBV among pregnant women attending different antenatal clinics in Unguja, Zanzibar hindering its control efforts. Therefore, this study determined the prevalence of Hepatitis B surface antigens (HBsAg) and associated factors among pregnant women attending to antenatal care clinics in Unguja, Zanzibar. Methodology: A hospital based cross sectional study involved 270 pregnant women attending to antenatal care clinics in Unguja, Zanzibar, conducted between May and July 2023. Data was collected using pretested structured data collection tool. Detection of hepatitis B surface antigen (HBsAg) was done by using immunochromatographic test. Obtained data analyzed by using STATA version 15. Results: The Mean (±SD) age of participants was 26.9(±5.7) years, majority of them were married 245(90.7%) and from urban 236(87.41%). The prevalence of HBsAg positivity among the pregnant women was 2.96% (8/270) [95% CI: 1.5%-5.2%]. Being HIV positivity (OR: 22, 95% CI: 2.7- 190.5, P=0.001), history of syphilis (OR: 12, 95% CI: 1.05- 156.2, P=0.046) were significant associated with HBsAg positivity Conclusion: Active hepatitis B infection among pregnant women in Unguja-Zanzibar is low according to WHO classification of hepatitis B infection severity and associated with HIV positivity and syphilis disease. Despite low prevalence of hepatitis B infection routine screening of HBsAg coupled with the vaccination of those at risk should be improved to prevent hepatitis B infection complications.
600			_xMedical Laboratory Sciences
600			_xMicrobiology & Immunology
700			_a Martha F. Mushi
700			_aMariam M. Mirambo
942			_2ddc _cCR
999			_c22918 _d22918