000			02825nam a22002897a 4500
001			CRECU/2282 04.05.2022
003			OSt
005			20240305193956.0
008			221213b |||||||| |||| 00| 0 eng d
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_bEnglish _cDLC
041			_aEnglish
041			_aKiswahili
100			_aNoela Thimothy Kimario _dCUHAS/BP/3000539/T/18 _947290 _eUndergraduate Ethical Clearance Certificate No. 2282/2022
245			_aAntibacterial activity of honey on Staphylococcus and Pseudomonas aeruginosa isolated from infected burn wounds at Bugando Medical Centre in Mwanza, Tanzania
260			_aMwanza, Tanzania: _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] : _c22.08.2022
300			_ax; 27 Pages
300			_aIncludes References and Appendices
520			_aAbstract: Introduction: Antimicrobial agents are essentially important in reducing the global burden of infectious diseases. However, the increase in bacterial resistance to the antimicrobial agents poses a very serious threat to public health and all kinds of antibiotics, including the major last resort drugs worldwide. This study aimed at determine the antibacterial activity of honey against S. aureus, A. baumannii and P. aeruginosa commonly causing burn wound infection to reduce overuse of antibiotics and to decrease the increase of antimicrobial resistance. Methodology: This was laboratory based-experimental study which was conducted at the CUHAS Microbiology laboratory. Aimed to determine antibacterial activity of honey against archived samples of S. aureus, A. baumannii and P. aeruginosa originally isolated from infected burn wounds in burn unit at BMC. The antibacterial activity of commercially obtained raw honey from stinging bees was determined by well diffusion technique and the zone of inhibition was measured and recorded. Results: Raw honey exhibited both bacteriostatic and bactericidal activity against tested organism with an overall zone mean of inhibition was 10.4(±5.2) mm. Honey inhibited Gram-negative bacteria growth more than in Gram positive bacteria (P value=0.016), and susceptibility was highest in P. aeruginosa (P value=0.001) which was statistically significant. Conclusion: From the results obtained in this study, we can consider honey as a promising future antibacterial agent against Methicillin resistant Staphylococcus aureus, P. aeruginosa and A. baumannii which are notorious to treat in infected burn wounds.
600			_x Microbiology and Immunology _948529
700			_a Betrand Msemwa _919669
700			_aVitus Silago _919665
942			_2ddc _cCR
999			_c22657 _d22657