000			03255nam a22003257a 4500
001			CRECU/2261 27.04.2022
003			OSt
005			20240305193955.0
008			221212b |||||||| |||| 00| 0 eng d
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_bEnglish _cDLC
041			_aEnglish
041			_aKiswahili
100			_aAngela J Kandia _dCUHAS/BP/3000509/T/18 _947268
210			_2Research report submitted in Partial Fulfilment for the Award of Bachelor of Pharmacy Degree of the Catholic University of Health and Allied Sciences _aABBREVIATIONS BMC Bugando Medical Centre CUHAS Catholic University of Health and Allied Sciences E. coli Escherichia coli GNB Gram Negative Bacteria HP Hydrogen Peroxide IPC Infection Prevention and Control K. pneumoniae Klebsiella pneumoniae Min Minute MRSA Methicillin resistance Staphylococcus aureus MS Methylated Spirit MSSA Methicillin susceptible Staphylococcus aureus PCR Polymerase chain reaction PI Povidone Iodine QAC Quaternary ammonium compound S. aureus Staphylococcus aureus SSIs Surgical site infections
222			_aKey words: _bsusceptibility, antiseptics, MRSA, MSSA
245			_aSusceptibility of Staphylococcus aureus to Antiseptics used at Bugando Medical Centre in Mwanza Tanzania
260			_aMwanza, Tanzania: _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c27.04.2022
300			_aPages ix; 22
300			_aIncludes Refferences and Appendices
520			_aABSTRACT: Introduction: Antiseptic is a substance that destroys or inhibits the growth of microorganisms such as bacteria especially in or on living tissue such as skin or mucous membranes .Antiseptics is used mainly for prevention of different infections. Resistance to antiseptics has shown to increase recently and this has led to spread of germs and development of infections (SSIs) which results to increased morbidity, hospital costs, treatment failure and death. This study determined the Susceptibility of Staphylococcus aureus to antiseptics used at Bugando Medical Centre in Mwanza Tanzania. Methods: The susceptibility of 29 methicillin-resistant S. aureus (MRSA), 31 methicillin-sensitive S. aureus (MSSA) isolates from our hospital to three antiseptic agents which are 6% Hydrogen Peroxide (6% HP), 70% Methylated Spirit (70% MS) and 10% Povidone Iodine (10% PI) was determined by microtiter plate assay. Results: The susceptibility of S.aureus strains increased based on the exposure time towards used antiseptics. The susceptibility was high in MSSA strains compared to MRSA strains on all used antiseptics at all different times of exposure. Conclusion: From this study, increase in time of exposure of antiseptic was associated with high susceptibility rate for the tested bacterial isolates; this encourages increase in time of antiseptic exposure during skin decolonisation for better results.
600			_x Microbiology and Immunology _948529
600			_xPharmacy _926693
700			_aVitus Silago _919665
700			_aBertrand Msemwa _945721
942			_2ddc _cCR
999			_c22636 _d22636