000			02934nam a22001697a 4500
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100			_a Mariamu Ibrahim _d CUHAS/BP/ 3000330/T/16 _926686
245			_aPrescription pattern of antihypertensive drugs and Cough prevalent in each antihypertensive drug group among hypertensive patients attending Bugando Medical Centre, Mwanza Tanzania
260			_aMwanza, Tanzania: _bCatholic University of Health and Allied Sciences [CUHAS - Bugando] : _bPhone: +255 28 298 3384 : _b Fax: +255 28 298 3386 : _b Email: vc@bugando.ac.tz : _b Website: www.bugando.ac.tz : _c ©16th September 2021
300			_axi; 24 Pages
300			_aIncludes Refferences and Appendices
520			_aAbstract: Background: Hypertension is the leading cause of death globally, it account for 10.4 million deaths per year. Antihypertensive drugs are prescribed to reduce the morbidity and mortality caused by hypertension and its complications. Antihypertensive agents are classified into five major categories which are angiotensin receptor blocked, calcium channel blocker, and angiotensin converting enzyme inhibitors, beta blockers and thiazide diuretics. Methodology: We conducted a cross sectional study among hypertensive patients aged ≥18 years and above who attend the outpatients’ cardiovascular clinic. An interviewer-based questionnaire was used to collect demographic information of prescription pattern of antihypertensive drugs and the prevalence of cough in each antihypertensive drug group. The data obtained was entered into the Microsoft excel for cleaning then transferred into STATA for statistical analysis. Results: 117 participants were included of which 77(65.8%) were female and 40 (34.2%) were male. This study shows that most of the patients were on combination therapy of antihypertensive drugs 63.2%, while 36.8% were using monotherapy. There was no cough among the hypertensive patients who were using angiotensin converting enzymes inhibitor with calcium channel blocker or beta blocker. The prevalence of cough was high in patients using angiotensin converting enzyme inhibitors as a monotherapy. Conclusion: This study revealed that 36.8% of hypertensive patients were using monotherapy (Angiotensin receptor blockers, calcium channel blockers, diuretics, beta blockers and vasodilator) and 44.4% were using two combination therapy and 18.8% were using three combination antihypertensive therapy. The prevalence of cough was high in patients who were using angiotensin converting enzyme inhibitors as a monotherapy. In two drug combination the prevalence of cough was high in patients using beta blocker and diuretic, while in three combination it was high in combination of angiotensin receptor blocker, diuretic and vasodilator.
600			_xInternal Medicine _915587
600			_xPharmacy _926693
700			_aSarah Matuja _926688
942			_2ddc _cCR
999			_c22194 _d22194