000			02251nam a22001697a 4500
008			210816b |||||||| |||| 00| 0 eng d
100			_aKyamwangile, Jenita. Rweyemamu _922054 _dCUHAS/BP/3000392/T/16
245			_a Complaints reported and awareness of gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs at Bugando Medical Centre, Mwanza, Tanzania
260			_aMwanza, Tanzania: _bCatholic University of Health and Allied Sciences [CUHAS - Bugando] : _bPhone: +255 28 298 3384 _b Fax: +255 28 298 3386 _b Email: vc@bugando.ac.tz _b Website: www.bugando.ac.tz _c©2020
300			_axi; 35 Pages
300			_aIncludes Refferences and Appendices
520			_aAbstract: Background: Non-steroidal inflammatory drugs (NSAIDs) are group of medicine that relieve pain and fever and reduce inflammation. Long term using of NSAIDs may lead to gastro intestinal damage vary from erosion and sub mucosal hemorrhage to ulceration also associated with occult blood protein. This caused by inhibition of prostaglandin synthesis which prevents stomach mucosa from being eroded by its own acid also can be cause by physiochemical of NSAIDs. Methodology: The study conducted by using cross-sectional descriptive study to determine the awareness of patient about adverse effect of NSAIDs based on gastrointestinal damage. The patient from orthopedic and physiotherapy department at Bugando Medical Centre were enrolled and data from answered questionnaires was entered to Microsoft and exported to SPSS for analysis. Result and discussion: About 219(56.9%) were not aware gastrointestinal damage induced by use of non-steroidal anti-inflammatory drugs. 43.1% complaints to have stomach pain after using NSAIDs. Also frequency of concomitant use of gastro protective was low only 34.5% of patients were using PPI. Conclusion and Recommendation: Majority of patients were not aware of gastrointestinal damage induced by non-steroidal anti-inflammatory drug and those who were aware get information after getting side effect. Education should be given to promote proper use of NSAIDs.
600			_xPharmacy _926693
600			_xDrugs _928380
700			_a Katabalo, Deogratias _919789
942			_2ddc _cCR
999			_c21820 _d21820