000			03100nam a22001817a 4500
001			CUHAS/BP/3000227/T/15
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100			_a Jacob, Fabiano. Epifani _dCUHAS/BP/3000227/T/15 _920957 _eUndergraduate Ethical Clearance Certificate No. 1023/2019
245			_aPrescription Pattern of Anticoagulants Among Ambulatory Patients With Coagulation Disorders at Bugando Medical Centre.
260			_aMwanza, Tanzania: _bCatholic University of Health and Allied Sciences [CUHAS - Bugando] : _bPhone: +255 28 298 3384 : _b Fax: +255 28 298 3386 : _b Email: vc@bugando.ac.tz : _bWebsite: www.bugando.ac.tz : _c ©12.09.2019
300			_a x; 16 Pages
300			_aIncludes References and Appendices
520			_aAbstract: Background: Anticoagulants are essential life-saving drugs mainly prescribed to cardiovascular patients to prevent coagulation of blood and increase clotting time. Since anticoagulants prevents formation of thrombi which when formed in vein, artery or intracardium can cause problems in obstruction, distal embolism and affect blood circulation. The recent development and marketing of novel direct oral anticoagulants (DOACs) represents a paradigm shift in the management of patients requiring long-term Anticoagulation. Hence the pattern of anticoagulants should be assessed to know the utilization of anticoagulants in hospital setting. Methods: A retrospective cross-sectional study was conducted in Bugando Medical Centre where systematic sampling was used to retrieve data from patient’s medical records from 1st January 2018 to 31st December 2018 and then filled the required information to the standardized checklist prepared finally analysed by STATA version 13. Results and Discussion: A total of 512patient’s files respectively reviewed out of the 412 files of ambulatory patients with coagulation disorders available. The most common anticoagulant prescribed to the ambulatory patient with coagulation disorder was rivaroxaban 51.97%, warfarin 45.3% and LMWH 2.63%. Also Anticoagulants agent were commonly prescribed for DVT by 26.3%, other VE&T 18.3%, PE 9.9%, AF 15.1%, Arterial Embolism and Thrombosis 3.29%, Embolism and Thrombosis of lower Extremities 3.29%, Embolism and Thrombosis 5.92% 5.92%, Disease of Mitral Valve 8.55%, occlusion of cerebral arteries 1.96%. The results obtained from the study is likely similar to the study done in Ethiopia where DVT and PE were most common indications. Some as study Nigeria and Kenya. Also is the study done in Ethiopia showed most commonly used anticoagulant were warfarin and enoxaparin. Conclusion and recommendation: The study shows that there is paradigm shift of management of coagulation disorders since development of Novel Direct Oral Anticoagulants like Rivaroxaban, this results are just for ambulatory patients hence there is need of doing the study on utilization of anticoagulants for in-patients.
600			_xPharmacy _926693
600			_xInternal Medicine _915587
700			_a Kalokola, Fredrick _920958
942			_2ddc _cCR
999			_c20950 _d20950