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100			_a Sospeter, Wilson _dCUHAS/BM/ 1000081/T/13 _920222
245			_a Seroprevalence and Associated Factors of Human Brurellosis Among Agropastoral Communities in Sengerema District, Mwanza, Tanzania.
260			_aMwanza, Tanzania: _bCatholic University of Health and Allied Sciences [CUHAS - Bugando]: _bPhone: +255 28 298 3384 : _bFax: +255 28 298 3386 : _b Email: vc@bugando.ac.tz : _b Website: www.bugando.ac.tz : _c ©2016
300			_a vii; 25 Pages
300			_aIncludes Refferences and Appendices
520			_aAbstract: Background and Objectives: Brucellosis is a public health concern and one of the neglected zoonotic disease especially in agro pastoral communities. Despite its importance there is limited information on the magnitude of this infections in the communities. This study was designed to determine seroprevalence and associated factors of human brucellosis among agro-pastoral communities. Methods: A cross sectional community based study was conducted from May to July 2016 by using achieved sera from 382 participants from agro-pastoral communities in Sengerema, Mwanza. Socio-demographic and clinical data were obtained using structured data collection tool. Detection of B.abortus and B.melitensis antibodies were done by using agglutination test. Data was analyzed by using STATA version 11.0 software. Results: The median age of participants was 30 (IQR: 15-40) years. Overall seroprevalence of brucella antibodies was found to be 14.1% (54/382, 95% CI: 10.6-17.5). Seroprevalence of B.melitensis antibodies was found to be 11% (42/382) while for B.abortus was 7% (26/282). Seroprevalence anti brucella antibodies indicating of co-infection with both B.melitensis and B.abortus was found to be 3.6% (14/382, 95% CI: 1.7-5.4). Male sex (AOR: 2.87, 95%CI: 1.24-6.65, P=0.014) and touching goat placenta (AOR: 2.59, 95% CI: 1.07-6.2, P=0.035) were independently found to predict B.melitensis infection. Only male sex (AOR: 2.59, 95%CI: 1.24-5.40, P=0.011) was independently found to be associated with infection with either of the two species. Conclusion and Recommendation: Significant proportion if individuals in agro-pastoral communities in Sengerema is infected with Brucella spp. There is a need to have continuous brucellosis surveillance in various regions in Tanzania and to offer health education.
600			_xMicrobiology and Immunology _948529
700			_aMirambo, Mariam _919715
700			_aMshana, Stephen. E _919716
942			_2ddc _cCR
999			_c20398 _d20398