| 000 | 02474nam a22002657a 4500 | ||
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| 003 | OSt | ||
| 005 | 20240305193738.0 | ||
| 008 | 221126b |||||||| |||| 00| 0 eng d | ||
| 028 | _b Phone: +255 28 298 3384 | ||
| 028 | _b Fax: +255 28 298 3386 | ||
| 028 | _b Email: vc@bugando.ac.tz | ||
| 028 | _b Website: www.bugando.ac.tz | ||
| 040 |
_bEnglish _cDLC |
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| 041 | _aEnglish | ||
| 100 |
_aMaryam Amour _945555 |
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| 245 | _aMedical management of acute loss of vision in tuberculous meningitis: A case report | ||
| 260 |
_aMwanza, Tanzania: _b Elsevier & _bCatholic University of Health and Allied Sciences [CUHAS – Bugando] _c2020/5/1 |
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| 300 | _aPages 100145 | ||
| 490 | _vJournal of Clinical Tuberculosis and Other Mycobacterial Diseases Volume 19 | ||
| 520 | _a Abstract: Objectives: Intravesical Bacillus Calmette-Guérin (BCG) treatment for superficial bladder cancer is interrupted in approximatively 8% of cases as a result of complications. The objective is to report the severe related complications of Bacillus Calmette-Guérin (BCG) following an intravesical instillation for bladder tumor encountered at our institution for the past 5 years. Methods: Medical records of a tertiary teaching hospital, located in Beirut, Lebanon, were retrospectively analyzed from June 2014 to June 2019 searching for severe related complications of BCG. A comprehensive review of articles on this subject was conducted. Results:The incidence of severe systemic adverse events related to BCG instillation was 1.5% (5 out of 332 patients). A total of five patients were found to have a severe BCG related complication, with fever, chills, and irritative urinary signs being the most frequent symptoms. All patients received antituberculosis therapy (Isoniazid, Rifampin and Ethambutol). Two were put on add-on corticosteroids. Three patients had a computed tomography scan image in favor of an infection. Two patients had a favorable outcome, three patients died. Conclusion: BCG severe adverse events were mostly seen in patients with a traumatic instillation. Treatment used at our institution was similar to most cases reported in the literature. A standardized diagnostic and treatment approach should be implemented to help physicians tackle these life-threatening complications. | ||
| 700 |
_aSarah Shali Matuja _946032 |
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| 700 |
_aJerome H Chin _946035 |
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| 856 | _uhttps://doi.org/10.1016/j.jctube.2020.100145 | ||
| 942 |
_2ddc _cVM |
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| 999 |
_c19732 _d19732 |
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