000 02548nam a22003137a 4500
003 OSt
005 20240305193735.0
008 221123b |||||||| |||| 00| 0 eng d
028 _b Phone: +255 28 298 3384
028 _b Fax: +255 28 298 3386
028 _bEmail: vc@bugando.ac.tz
028 _b Website: www.bugando.ac.tz
040 _bEnglish
_cDLC
041 _aEnglish
100 _aPaulina Manyiri
_922702
222 _aMycobacteremia Mortality Fever HIV
245 _aPrevalence and factors associated with Mycobacteremia and mortality among febrile HIV infected patients in Mwanza, Tanzania
260 _aMwanza, Tanzania:
_b Elsevier &
_b Catholic University of Health and Allied Sciences [CUHAS – Bugando]
_c2018/5/1
300 _a Pages 69-71
490 _v International Journal of Infectious Diseases Volume 70
520 _aAbstract: Objectives: This study investigated the prevalence and factors associated with mycobacteremia and mortality among febrile HIV infected patients in developing countries. Methods: A hospital based cross-sectional study was conducted among febrile HIV patients admitted at Bugando Medical centre and Sekou Toure hospital between November 2016 and March 2017. Blood culture was done on BACTEC Myco/F Lytic bottles. Clinical and demographic data were collected using a pre-tested data collection tool. Results: A total of 154 patients with the mean age of 41.5 ± 12.2 were enrolled. Females formed the majority, 93 (60%) of the study participants. The prevalence of Mycobacteremia was 3.3% while that of other bacteria was 8.4%. Age (p = 0.03), recent HIV diagnosis (p = 0.005), not taking HAART (p = 0.031) and low CD4+ count (p = 0.002) were significantly associated with Mycobacteremia. Factors significantly associated with 14-day in-hospital mortality were advanced HIV infection (p < 0.001), poor ART adherence (p < 0.001), low CD4+ (p = 0.0002) and Mycobacteremia (p = 0.007). Conclusion: The prevalence of Mycobacteremia was low; however, it was significantly associated with mortality. Mycobacteremia should be suspected in high risk febrile HIV infected individuals followed by early appropriate treatment in order to reduce associated morbidity and mortality.
700 _a Rodrick Kabangila
_923057
700 _a Christa Kasang
_923005
700 _aMartha F Mushi
_919663
700 _aMariam M Mirambo
_922927
700 _a Stephen E Mshana
_915820
856 _uhttps://doi.org/10.1016/j.ijid.2018.03.009
942 _2ddc
_cVM
999 _c19649
_d19649