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| 005 | 20240305193735.0 | ||
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| 028 | _b Phone: +255 28 298 3384 | ||
| 028 | _b Fax: +255 28 298 3386 | ||
| 028 | _b Email: vc@bugando.ac.tz | ||
| 028 | _b Website: www.bugando.ac.tz | ||
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_bEnglish _cDLC |
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| 041 | _aEnglish | ||
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_aRuth W Kiiti _945743 |
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| 245 | _aResearch Article Antimicrobial Resistance Profiles of Escherichia coli Isolated from Broiler and Layer Chickens in Arusha and Mwanza, Tanzania | ||
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_aMwanza, Tanzania: _bHindawi & _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c22 October 2021 |
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| 300 | _aPages 1-9 | ||
| 490 | _vHindawi International Journal of Microbiology Volume 2021, Article ID 6759046, | ||
| 520 | _aThe rise in the spread of antibiotic-resistant pathogens such as Escherichia coli is one of the very important dynamics off-putting treatment and prophylaxis possibilities, hence posing a threat to the modern human medicine, veterinary medicine, and food safety. (erefore, the aim of this study was to determine antimicrobial resistance profiles in E. coli isolates obtained from broiler and layer chickens in Mwanza and Arusha regions in Tanzania. A cross-sectional study was carried out from February to March, 2021, in 402 poultry farms in Mwanza (201) and Arusha (201) regions in Tanzania. All samples that tested positive for E. coli were confirmed using MALDI-TOF MS, and two hundred and four (204) E. coli isolates were randomly chosen and subjected to antimicrobial susceptibility testing by disc diffusion method. Data were entered in Microsoft Excel® and analyzed using SPSS version 20. Isolates were tested against seven antimicrobial agents belonging to seven classes of antimicrobials. All the tested isolates (n � 204) were resistant to at least one antimicrobial agent. Overall, the highest resistance was observed in ampicillin (100%), whereas the lowest resistance was recorded for gentamicin (10.3%). Majority of the isolates (86.76%) were multidrug resistant. Antimicrobial resistance of E. coli to four classes of antimicrobial agents was the highest in this study (31.1%). Six of the 177 tested isolates (2.9%) were resistant to the seven classes of antimicrobial agents. 21 of the 204 (10.29%) isolates were ESBL producers where 21/21 (100%) isolates expressed blaTEM genes and only two isolates expressed (2/21) blaCTX-M gene. (e isolates obtained in this study displayed high resistance to commonly used antimicrobial agents in veterinary and human medicine. (is implies that there is existence of practices that accelerate antimicrobial resistance in the production of the sampled birds and therefore integration of appropriate use of antimicrobial agents and other measures that curb the spread of resistant genes is necessary | ||
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_a Erick V Komba _945744 |
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_a Peter L Msoffe _945745 |
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_aStephen E Mshana _915820 |
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_a Mark Rweyemamu _923607 |
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_aMecky IN Matee _945585 |
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| 856 | _uhttps://doi.org/10.1155/2021/6759046 | ||
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_2ddc _cVM |
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_c19642 _d19642 |
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