000			02919nam a22003137a 4500
003			OSt
005			20240305193732.0
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028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_bWebsite: www.bugando.ac.tz
040			_bEnglish _cDLC
041			_aEnglish
100			_aPius G Horumpende _945586
222			_a Antibiotic prescription Antibiotic stewardship Point prevalence survey Antimicrobial resistance Tanzania
245			_aPoint prevalence survey of antimicrobial use in three hospitals in North-Eastern Tanzania
260			_aMwanza, Tanzania: _bBioMed Central & _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c07 September 2020
300			_aPages 1-6
490			_v Antimicrobial Resistance & Infection Control Volume 9 Issue 1
520			_aAbstract Background: Antimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania. Methods: A PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 h and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day. Results: A total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. Ceftriaxone (n = 94, 29.8%), metronidazole (n = 79, 23.9%) and other antibiotics belonging to the penicillin class (n = 89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases. Conclusion: Our study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.
700			_aStephen E Mshana _915820
700			_a Elise F Mouw _945654
700			_a Blandina T Mmbaga _944885
700			_a Jaffu O Chilongola _945587
700			_a Quirijn de Mast _945655
856			_uhttps://doi.org/10.1186/s13756-020-00809-3
942			_2ddc _cVM
999			_c19557 _d19557