000			02887nam a22003137a 4500
003			OSt
005			20240305193727.0
008			221115b |||||||| |||| 00| 0 eng d
022			_aprint ISSN: 2141-9248
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aH Mbena _923710
222			_a Human immunodeficiency virus seroconversion, Pregnant women, Tanzania
245			_aHuman immunodeficiency virus seroconversion and associated risk factors among pregnant women delivering at Bugando medical Center in Mwanza, Tanzania
260			_aMwanza, Tanzania: _bAnnals of Medical and Health Sciences Research & _bCatholic University of Health and Allied Sciences [CUHAS – Bugando] _c2015-02-03
300			_a Pages 733-737
490			_vAnnals of Medical and Health Sciences Research Volume 4 Issue 5
520			_aAbstract Background: Routine testing for human immunodeficiency virus (HIV) among pregnant women is done early during antenatal care (ANC) in Tanzania, but retesting for the women found negative is rarely done at term or during delivery. Aim: This study aimed at determining the magnitude and risk factors associated with HIV seroconversion among pregnant women delivering at Bugando Medical Center (BMC). Subjects and Methods: This cross.sectional study was conducted from January to March 2013 involving 400 pregnant women who tested HIV negative during ANC. These were re.tested during delivery, and those found positive (and their babies) were given antiretroviral therapy (ART) prophylaxis. All exposed babies were tested by polymerase chain reactions (DNAPCR) at 1 month of age. Sociodemographic and clinical characteristics were collected using a structured questionnaire and patientsf files. Data were analyzed using SPSS version 17.0 software. Results: Of 400 pregnant women (mean age 26.4 [5.73] years) enrolled, HIV seroconversion was found in 5.3% (21/400). Upon multivariate logistic regression analysis, polygamous marriage (P < 0.001) and history of syphilis during ANC visit (P < 0.001) were found to be independent predictors of HIV seroconversion among pregnant women delivering at BMC. One of the 21 babies (4.8%) born of HIV seroconverted women was confirmed to be HIV infected. Conclusion: The high rate of HIV seroconversion found in this study implies that HIV re.testing should be an enduring exercise. This will allow timely provision of ART prophylaxis to HIV seroconverted women and their exposed babies and thus, prevent mother to child transmission of HIV.
700			_a J Seni _923416
700			_aA Kajura _945376
700			_a D Matovelo _945377
700			_aA Kihunrwa _945378
856			_u 10.4103/2141-9248.141539
942			_2ddc _cVM
999			_c19430 _d19430