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| 003 | OSt | ||
| 005 | 20240305193727.0 | ||
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| 028 | _b Phone: +255 28 298 3384 | ||
| 028 | _b Fax: +255 28 298 3386 | ||
| 028 | _b Email: vc@bugando.ac.tz | ||
| 028 | _bWebsite: www.bugando.ac.tz | ||
| 040 | _cDLC | ||
| 041 | _aEnglish | ||
| 100 |
_aMariam M Mirambo _922927 |
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| 222 | _a Parvovirus B19 Pregnant women Tanzania | ||
| 245 | _aThe magnitude and correlates of Parvovirus B19 infection among pregnant women attending antenatal clinics in Mwanza, Tanzania | ||
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_aMwanza, Tanzania: _b BioMed Central & _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c 07 June 2017 |
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| 300 | _aPages 1-7 | ||
| 490 | _vBMC pregnancy and childbirth Volume 17 Issue 1 | ||
| 520 | _aAbstract Background: Human parvovirus B19 (B19) infection has been associated with congenital infection which may result into a number of the adverse pregnancy outcomes. The epidemiology and the magnitude of B19 infections among pregnant women have been poorly studied in developing countries. This study was done to establish preliminary information about the magnitude of B19 among pregnant women attending antenatal clinics in the city of Mwanza, Tanzania. Methods: A cross-sectional study was conducted between December 2014 and June 2015 among 258 pregnant women attending two antenatal clinics representing rural and urban areas in the city of Mwanza. Socio-demographic data were collected using structured data collection tool. Specific B19 IgM and IgG antibodies were determined using indirect enzyme linked immunosorbent assay kits (DRG Instruments GmbH, Germany). Data were analyzed using STATA version 11 software. Results: The median age of study participants was 21 IQR (19–25) years. Of 253 pregnant women; 116(44.96%), 109(42.25%) and 33(12.79%) were in the first, second and third trimester respectively. The majority 168(66.4%) of women were from urban areas. Of 253 pregnant women, the overall prevalence of IgM was 83(32.8%) while that of IgG was 142(55.0%) among 258 women tested. A total of 50(19.4%) women were positive for both IgG and IgM indicating true IgM positive. History of baby with low birth weight (OR: 10, 95% CI: 1.82–58.05, P = 0.01) was independent predictor of B19 IgG seropositivity and being at the third trimester was protective (OR: 0.38, 95% CI: 0.16–0.92, P = 0.03). The IgG titers were found to decrease significantly as gestational age increases (Spearman’s rho = −0.2939, p = 0.0004) Conclusion: More than a half of pregnant women in Mwanza city are B19 IgG sero-positive with about one third of these being B19 IgM seropositive. Further studies to determine the impact of B19 infections among pregnant women and their newborns are recommended in developing countries. | ||
| 700 |
_aFatma Maliki _945318 |
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| 700 |
_a Mtebe Majigo _922970 |
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| 700 |
_aMartha F Mushi _919663 |
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_a Nyambura Moremi _922727 |
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_a Jeremiah Seni _919633 |
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_a Dismas Matovelo _922780 |
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_a Stephen E Mshana _915820 |
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| 856 | _uhttps://doi.org/10.1186/s12884-017-1364-y | ||
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_2ddc _cVM |
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_c19416 _d19416 |
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