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028			_bPhone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aElichilia R Shao _923409
222			_aCost-free hepatitis B vaccine, Prevention, Healthcare workers, vaccination coverage, Low income countries, Tanzania.
245			_aUptake of Cost-Free Hepatitis B Vaccination among Healthcare Workers in Northern Tanzania
260			_aMwanza: _cTanzania Medical Journal & _c Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] _b2021/4/29
300			_aPages 39-56
490			_vTanzania Medical Journal Volume 32 Issue 2
520			_a Abstract Background: The World Health Organization and other global agencies recommend all healthcare workers (HCWs) to get vaccinated against hepatitis B virus before enrolment to clinical work. There are limited data in low-income countries on hepatitis B virus vaccination coverage among HCWs, which set back WHO Hepatitis B Elimination Strategy 2016-2021. The aim of this study was to determine the prevalence of hepatitis B virus vaccination uptake and associated factors among HCWs from a tertiary and teaching hospital in northern Tanzania. Methods: A cross-sectional study was conducted among HCWs at Kilimanjaro Christian Medical Centre a referral and teaching hospital from August 2016 to June 2017. Questionnaire based interviews were used to obtain information about HCWs’ demographic characteristics, occupation risks and other invasive procedures such as intravenous, and intramuscular injections and knowledge of Hepatitis B Virus (HBV) infection. Multivariable logistic regression was used to determine factors associated with Engerex DNA-recombinant hepatitis B vaccine uptake. Results: About two third 295 (67.4%) of 438 participants had received HBV vaccination. Among those who ever received HBV vaccination (n=295), 205 (70.5%) received 3 shots, 57 (19.5%) received 2 shots and 33 (10%) received 1 shot. HCWs working in clinical areas had 79% higher odds of vaccine uptake compared to those who were not (OR=1.79, 95%CI 1.11, 2.89). Ever having intravenous and intramuscular injections significantly increased the odds of vaccination uptake compared to those who never had (OR=2.21, 95%CI 1.33, 3.66) and (OR=2.42, 95%CI 1.36, 4.28) respectively. Also, HCWs with a fair and good knowledge on HBV infection had over three times higher odds of vaccine uptake compared to those with poor knowledge (OR=3.08, 95%CI 1.90, 5.01) and (OR=3.07, 95%CI 1.75, 5.40), respectively. After adjusting for other factors, those that remained to be significantly associated with HBV vaccine uptake were area of specialty and knowledge on HBV infection. Conclusion: The current Engerex DNA-recombinant hepatitis B vaccine coverage among HCWs at KCMC, referral and teaching hospital in North-eastern Tanzania was only 67.4% despite of it been given free of charge. Factors that were associated with HBV vaccine uptake include area of specialty and knowledge of participants on HBV infection and vaccination. We encourage continuous medical education among HCWs about importance of hepatitis B vaccination. We also recommend hepatitis B vaccination as pre-employment requirement for HCWs as well as doing antibody titer determination post vaccination.
700			_aInnocent B Mboya _945281
700			_a Furaha Lyamuya _945282
700			_aElizabeth Temu _945283
700			_a Mercy Nkwama _945284
700			_a Semvua Kilonzo _923124
700			_a Daniel W Gunda _922748
700			_aBalthazar B Nyombi _944890
700			_a Gissela Nyakunya _945285
700			_aAkrabi Huda _945286
700			_a Sarah Urasa _945287
700			_aKajiru Kilonzo _945288
700			_a Venance Maro _945289
856			_uhttps://doi.org/10.4314/tmj.v32i2.424
942			_2ddc _cVM
999			_c19390 _d19390