000			02481nam a22003257a 4500
003			OSt
005			20240305193722.0
008			221107b |||||||| |||| 00| 0 eng d
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aJeremiah Seni _919633
245			_aDraft genome sequence of a multidrug-resistant caprine isolate of Staphylococcus cohnii subsp. urealyticus from Tanzania encoding ermB, tet (K), dfrG, fusF and fosD
260			_aMwanza: _bElsevier & _b Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c 2019/9/1
300			_a Pages 163-165
490			_vJournal of global antimicrobial resistance Volume 18
520			_aAbstract Objectives: Coagulase-negative staphylococci such as Staphylococcus cohnii are opportunistic pathogens of humans and animals. A multidrug-resistant isolate of S. cohnii subsp. urealyticus (073AN) was isolated from the nasal cavity of a healthy goat in Tanzania. This study produced and analysed a draft genome sequence of strain 073AN to investigate the genetic basis for antimicrobial resistance in this isolate. Methods: Strain 073AN was sequenced using HiSeq 2000 technology, sequencing reads were assembled using Velvet, and the genome was annotated using Prokka. Results: The draft genome of strain 073AN is 2 677 652 bp in size with a GC content of 32.5%. The isolate was resistant to several classes of antimicrobials, which correlated with the presence of known antimicrobial resistance genes. Of particular note, the draft genome sequence of strain 073AN represents the first report of fosD in S. cohnii and the first descriptions of fosD and fusF in Africa. Conclusion: The draft genome sequence of S. cohnii subsp. urealyticus 073AN released here provides an insight into the antimicrobial resistance determinants found in this species and in Tanzania and offers a valuable resource for further studies on staphylococcal genomics and antimicrobial resistance.
700			_a Stephen E Mshana _915820
700			_aFelician Msigwa _945127
700			_aShabani Iddi _926664
700			_aHumphrey Mazigo _930367
700			_a Julian Parkhill _945128
700			_aMark A Holmes _945129
700			_a Gavin K Paterson _945130
856			_uhttps://doi.org/10.1016/j.jgar.2019.07.006
942			_2ddc _cVM
999			_c19313 _d19313