000			03178nam a22002897a 4500
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022			_aeISSN: 1821-9241
022			_a print ISSN: 1821-6404
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_bEmail: vc@bugando.ac.tz
028			_bWebsite: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aFlorah Bukindu _945096
222			_a preventive chemotherapy, uptake, Schistosoma mansoni, soil-transmitted helminths, Tanzania
245			_aPrevalence of Schistosoma mansoni and soil transmitted helminths and factors associated with uptake of preventive chemotherapy among school children in Sengerema District in north-western Tanzania
260			_aMwanza: _bTanzania Journal of Health Research & _bTanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c2016-01-10
490			_vTanzania Journal of Health Research Volume 18 Issue 1
520			_aAbstract Background: The control of intestinal schistosomiasis and soil transmitted helminths (STH) in Tanzania focuses on reducing morbidities through the treatment of infected and at risk populations, especially schoolchildren with praziquantel (PZQ) and albendazole (ALB). However, in some areas, the uptake of interventions is low. The objective of this study was to determine factors associated with the uptake of preventive chemotherapy and, secondarily, the prevalence of Schistosoma mansoni and soil-transmitted helminths' infections in Sengerema District of north western Tanzania. Methods: This cross-sectional study was conducted among 625 randomly selected school children aged 8-18 years from Sengerema district. A questionnaire was used to collect information on the reported uptake of PZQ/ALB. Single stool samples were collected, processed and examined for the presence of eggs pf S. mansoni and soil-transmitted helminths using Kato Katz technique. Results: The self-reported uptake of preventive chemotherapy was 95.6% (95%CI; 92.78-98.49). Provision of food (AOR= 25.25, 95%CI: 5.28-120.49, p<0.001) and information about the anti-helminthic drug prior to taking it (AOR =14.24, 95%CI: 3.23-62.72, p<0.001) were associated with a high reported uptake of preventive chemotherapy. The overall prevalence of S. mansoni and geometrical mean of eggs per gram (EPG) of faeces were 36.64% (95%CI: 21.55 -62.29) and 229.47 EPG (202.73-259.86). The prevalence of STH was 10.88% (95%CI; 7.52-15.75). Conclusion: The high reported uptake of preventive chemotherapy was associated with provision of food and information about the drugs prior to their administration. However, S. mansoni and soil-transmitted infections are still a public health concern in the study area. Integrating health education in mass drug administration campaigns will allow provision of other complementary public preventive measures to reduce the burden of these infections.
700			_a Domenica Morona _922989
700			_aHumphrey D Mazigo _922835
856			_uhttps://doi.org/10.4314/thrb.v18i1.7
942			_2ddc _cVM
999			_c19297 _d19297