000			03164nam a22003137a 4500
003			OSt
005			20240305193720.0
008			221103b |||||||| |||| 00| 0 eng d
022			_a1756-0500
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aHumphrey D Mazigo _922835
222			_a Fever history of fever parasitological diagnosis western Tanzania
245			_aConfirmed malaria cases among children under five with fever and history of fever in rural western Tanzania
260			_aMwanza: _b BioMed Central & _b Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c13 September 2011
300			_a Pages 1-6
490			_vBMC research notes Volume 4 Issue 1
520			_aAbstract Background The World Health Organization recommends that malaria treatment should begin with parasitological diagnosis. This will help to control misuse of anti-malarial drugs in areas with low transmission. The present study was conducted to assess the prevalence of parasitologically confirmed malaria among children under five years of age presenting with fever or history of fever in rural western Tanzania. A finger prick blood sample was obtained from each child, and thin and thick blood smears were prepared, stained with 10% Giemsa and examined under the light microscope. A structured questionnaire was used to collect each patient's demographic information, reasons for coming to the health center; and a physical examination was carried out on all patients. Fever was defined as axillary temperature ≥ 37.5°C. Findings A total of 300 children with fever or a history of fever (1 or 2 weeks) were recruited, in which 54.3% (163/300, 95%CI, 48.7-59.9) were boys. A total of 76 (76/300, 25.3%, 95%CI, 22.8 - 27.8) of the children had fever. Based on a parasitological diagnosis of malaria, only 12% (36/300, 95%CI, 8.3-15.7) of the children had P. falciparum infection. Of the children with P. falciparum infection, 52.7% (19/36, 95%CI, 47.1-58.3) had fever and the remaining had no fever. The geometrical mean of the parasites was 708.62 (95%CI, 477.96-1050.62) parasites/μl and 25% (9/36, 95%CI, 10.9 -- 39.1) of the children with positive P. falciparum had ≥ 1001 parasites/μl. On Univariate (OR = 2.13, 95%CI, 1.02-4.43, P = 0.044) and multivariate (OR = 2.15, 95%CI, 1.03-4.49) analysis, only children above one year of age were associated with malaria infections. Conclusion Only a small proportion of the children under the age of five with fever had malaria, and with a proportion of children having non-malaria fever. Improvement of malaria diagnostic and other causes of febrile illness may provide effective measure in management of febrile illness in malaria endemic areas.
700			_aWilfred Meza _945048
700			_aEmanuella E Ambrose _945049
700			_aBenson R Kidenya _922909
700			_a Eliningaya J Kweka _944252
856			_uhttps://doi.org/10.1186/1756-0500-4-359
942			_2ddc _cVM
999			_c19266 _d19266