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022			_a1756-3305
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cDLC
041			_aEnglish
100			_aHumphrey D Mazigo _922835
222			_a Malaria Schistosomiasis Praziquantel Helminth Infection Infection Intensity
245			_aCo-infections with Plasmodium falciparum, Schistosoma mansoni and intestinal helminths among schoolchildren in endemic areas of northwestern Tanzania
260			_aMwanza: _b BioMed Central & _b Tanzania Catholic University of Health and Allied Sciences [CUHAS – Bugando] _c19 May 2010
300			_aPages 1-7
490			_vJournal Parasites & vectors Volume 3 Issue 1
520			_aAbstract Background Malaria, schistosomiasis and intestinal helminth infections are causes of high morbidity in most tropical parts of the world. Even though these infections often co-exist, most studies focus on individual diseases. In the present study, we investigated the prevalence of Plasmodium falciparum- malaria, intestinal schistosomiasis, soil-transmitted helminth infections, and the respective co-infections, among schoolchildren in northwest Tanzania. Methods A cross sectional study was conducted among schoolchildren living in villages located close to the shores of Lake Victoria. The Kato Katz technique was employed to screen faecal samples for S. mansoni and soil-transmitted helminth eggs. Giemsa stained thick and thin blood smears were analysed for the presence of malaria parasites. Results Of the 400 children included in the study, 218 (54.5%) were infected with a single parasite species, 116 (29%) with two or more species, and 66 (16.5%) had no infection. The prevalences of P. falciparum and S. mansoni were 13.5% (95% CI, 10.2-16.8), and 64.3% (95% CI, 59.6-68.9) respectively. Prevalence of hookworm infection was 38% (95% CI, 33.2-42.8). A. lumbricoides and T. trichiura were not detected. Of the children 26.5% (95% CI, 21.9-30.6) that harbored two parasite species, combination of S. mansoni and hookworm co-infections was the most common (69%). Prevalence of S. mansoni - P. falciparum co-infections was 22.6% (95%CI, 15.3-31.3) and that of hookworm - P. falciparum co-infections 5.7% (95%CI, 2.6-12.8). Prevalence of co-infection of P. falciparum, S. mansoni and hookworm was 2.8% (95%CI, 1.15-4.4). Conclusion Multiple parasitic infections are common among schoolchildren in rural northwest Tanzania. These findings can be used for the design and implementation of sound intervention strategies to mitigate morbidity and co-morbidity.
700			_a Rebecca Waihenya _944849
700			_aNicholas JS Lwambo _945014
700			_a Ladislaus L Mnyone _945015
700			_aAneth M Mahande _945016
700			_aJeremiah Seni _919633
700			_aMaria Zinga _926705
700			_a Anthony Kapesa _922819
700			_aEliningaya J Kweka _944252
700			_a Stephen E Mshana _915820
700			_a Jorg Heukelbach _923002
700			_aGerald M Mkoji _944850
856			_uhttps://doi.org/10.1186/1756-3305-3-44
942			_2ddc _cVM
999			_c19248 _d19248