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100 _aDaniel Wilfred Gunda (RIP)
_922878
245 _aPrevalence and Risk Factors of Mortality among Adult HIV Patients Initiating ART in Rural Setting of HIV Care and Treatment Services in North Western Tanzania: A Retrospective Cohort Study
260 _aMwanza, Tanzania
_bCatholic University of Health and Allied Sciences CUHAS - Bugando &
_b Hindawi Limited
_c2017
490 _vJournal of sexually transmitted diseases Volume 2017
520 _aIntroduction: HIV still causes high mortality despite use of ART. This study was designed to determine the prevalence and risk factors of mortality among HIV patients receiving ART in northwestern rural Tanzania. Methods: A retrospective study of HIV patients on ART was done at Sengerema in Mwanza, Tanzania. The data on demography, date of HIV diagnosis, WHO stage, opportunistic infections, CD4, hemoglobin, ART regimen, and time and outcome on treatment as dead or alive were collected and analyzed using STATA version 11. Results: In total, 740 patients were studied. The median age was 35 (27–42) years with female predominance of 465 (62.8%). Of the participants, 261 (35.3%) had WHO stages 3 and 4 diseases. Most participants, 258 (34.9%), had baseline CD4 counts< 200 cells/𝜇l. Deaths occurred in 86 (11.6%) patients which were independently associated with male gender (16.0% versus 9.0%, 𝑝= 0.015), being divorced (OR= 2.7, 𝑝< 0.001), WHO stages 3 and 4 (OR= 2.3, 𝑝= 0.05), CD4< 200 cells/𝜇l (OR= 3.4, 𝑝< 0.001), and severe anemia (OR= 6.6, 𝑝< 0.001). Conclusions: The mortality is high among HIV patients receiving ART in northwestern rural Tanzania. Universal testing could increase early diagnosis and treatment. A close follow-up of at-risk patients within the first year of ART could reduce the mortality of this subgroup of patients.
700 _aIgembe Nkandala
_922894
700 _aSemvua Bukheti Kilonzo
_922895
700 _a Boniface Bartholomew Kilangi
_922896
700 _aBonaventura Cornel Mpondo
_922897
856 _uhttps://scholar.google.com/citations?view_op=view_citation&hl=en&user=yZAiL9MAAAAJ&citation_for_view=yZAiL9MAAAAJ:3fE2CSJIrl8C
942 _2ddc
_cVM
999 _c18829
_d18829