000			02857nam a22002897a 4500
001			CUHAS/MMED/6000116/T/13
003			CUHAS/MMED/6000116/T/13
005			20240416133259.0
008			230204b |||||||| |||| 00| 0 eng d
028			_b Phone: +255 28 298 3384
028			_b Fax: +255 28 298 3386
028			_b Email: vc@bugando.ac.tz
028			_b Website: www.bugando.ac.tz
040			_cddc
041			_aEnglish
100			_aLukombodzo Elioth Lulandala _948337 _d[Male] _eCUHAS/MMED/6000116/T/13
245			_aSeroprevalence of Acute Rubella virus Infection and Associated Factors among Women Treated for Abortion Complications in Mwanza City Tanzania.
260			_aMwanza, Tanzania: _b Catholic University of Health and Allied Sciences [CUHAS – Bugando] : _cc2016
300			_a41 Pages
300			_aIncludes References and Appendices
520			_aAbstract: Background: Acute rubella virus infection in early pregnancy is often associated with poor pregnancy outcomes such as spontaneous abortion, stillbirth and wide range of multiples birth defects known as congenital rubella syndrome (CRS). Despite its importance the role of acute rubella virus infections among women with spontaneous abortion in most of developing countries is not clearly known. Objectives: This study for the first time in Mwanza aimed at determining seroprevalence and factors associated with acute rubella virus infection among women with spontaneous abortion. Methods: A cross sectional hospital based study involving 268 women with spontaneous abortion was conducted between November 2015 and April 2016 in four different hospitals in Mwanza city. For each participant about 4mls of bloodsample was collected; sera were extracted and stored at -40 cuntil processing. Acute rubella virus infection was determined by detection of rubella specific IgM antbodies by indirect enzyme linked immunosorbent assay (ELISA). Data analysis was done using STATA version 11 Results: The mean age of enrolled women was 26.3±5.6 years. The prevalence of acute rubella infection was found to be 3.4% (9/268). On multivariate logistic regression analysis; only residing in urban areas (OR: 5.65, 95% CI: 1.13-28.19, p=0.035) was found to predict acute rubella virus infection among women with diagnosis of spontaneous abortion in Mwanza city on multivariate logistic regression analysis. Conclusion: Considerable proportion of women residing in urban areas of Mwanza city with abortion complications are acutely infected with rubella virus which calls for the need to introduce screening and counselling these women as they attend antenatal clinics.
600			_xObstetrics and Gynaecology _947107
700			_aBalthazar Gumodoka _922910
700			_aMariam Mirambo _919596
700			_aDismas Matovelo _922780
942			_2ddc _cMP
999			_c18679 _d18679