| 000 | 04682cam a22005655i 4500 | ||
|---|---|---|---|
| 001 | 21664661 | ||
| 003 | OSt | ||
| 005 | 20240305193056.0 | ||
| 006 | m |o d | | ||
| 007 | cr ||||||||||| | ||
| 008 | 160614s2016 gw |||| o |||| 0|eng | ||
| 010 | _a 2019741203 | ||
| 020 | _a9783319319735 | ||
| 024 | 7 |
_a10.1007/978-3-319-31973-5 _2doi |
|
| 035 | _a(DE-He213)978-3-319-31973-5 | ||
| 040 |
_aDLC _beng _epn _erda _cDLC |
||
| 072 | 7 |
_aPSC _2bicssc |
|
| 072 | 7 |
_aSCI072000 _2bisacsh |
|
| 072 | 7 |
_aPSC _2thema |
|
| 082 | 0 | 4 |
_a571.8 _223 |
| 245 | 0 | 0 |
_aMolecular Mechanisms of Cell Differentiation in Gonad Development / _cedited by Rafal P. Piprek. |
| 250 | _a1st ed. 2016. | ||
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2016. |
|
| 300 | _a1 online resource (XII, 434 pages 52 illustrations, 48 illustrations in color.) | ||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 490 | 1 |
_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v58 |
|
| 505 | 0 | _aEarly Development of the Gonads - Origin and Differentiation of the Somatic Cells of the Genital Ridges -- The formation and migration of primordial germ cells in mouse and man -- The Gonadal Supporting Cell Lineage and Mammalian Sex Determination: the Differentiation of Sertoli and Granulosa Cells -- Mesonephric cell migration into the gonads and vascularization are processes crucial for testis development -- Origin and Differentiation of Androgen-producing Cells in the Gonads -- Germ cell commitment to oogenic versus spermatogenic pathway - the role of retinoic acid -- Ovarian Folliculogenesis -- Control of oocyte growth and development by intercellular communication within the follicular niche -- Biology of the Sertoli cell in the Fetal, Pubertal and Adult Mammalian Testis -- Mechanisms Regulating Spermatogonial Differentiation -- Stem cells in mammalian gonads -- A Role of microRNAs in Cell Differentiation during Gonad Development -- The Battle of the Sexes: Human Sex Development and its Disorders -- Methods for the study of gonadal development. | |
| 520 | _aThis book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development. | ||
| 588 | _aDescription based on publisher-supplied MARC data. | ||
| 650 | 0 |
_aDevelopmental biology. _9472 |
|
| 650 | 0 | _aStem cells. | |
| 650 | 0 |
_aCytogenetics. _98193 |
|
| 650 | 0 | _aMolecular biology. | |
| 650 | 0 |
_aReproductive medicine. _98194 |
|
| 650 | 1 | 4 |
_aDevelopmental Biology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L18000 _9472 |
| 650 | 2 | 4 |
_aStem Cells. _0https://scigraph.springernature.com/ontologies/product-market-codes/L16010 |
| 650 | 2 | 4 |
_aCytogenetics. _0https://scigraph.springernature.com/ontologies/product-market-codes/B12040 _98193 |
| 650 | 2 | 4 |
_aMolecular Medicine. _0https://scigraph.springernature.com/ontologies/product-market-codes/B1700X _92150 |
| 650 | 2 | 4 |
_aReproductive Medicine. _0https://scigraph.springernature.com/ontologies/product-market-codes/H56002 _98195 |
| 700 | 1 |
_aPiprek, Rafal P. _eeditor. _98196 |
|
| 776 | 0 | 8 |
_iPrinted edition: _z9783319319711 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319319728 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319811673 |
| 830 | 0 |
_aResults and Problems in Cell Differentiation, _x0080-1844 ; _v58 _98197 |
|
| 906 |
_a0 _bibc _corigres _du _encip _f20 _gy-gencatlg |
||
| 942 |
_2ddc _cBK |
||
| 999 |
_c12762 _d12762 |
||