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| 006 | m |o d | | ||
| 007 | cr_||||||||||| | ||
| 008 | 181105s2019 nju ob 001 0 eng | ||
| 010 | _a 2018053075 | ||
| 020 |
_a9781119289210 _q(Adobe PDF) |
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| 020 |
_a9781119289227 _q(ePub) |
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| 020 |
_z9781119289197 _q(hardback) |
||
| 040 |
_aDLC _beng _erda _cDLC _dDLC |
||
| 042 | _apcc | ||
| 050 | 1 | 0 | _aRC600 |
| 060 | 1 | 0 | _aWD 305 |
| 082 | 0 | 0 |
_a616.97/806 _223 |
| 245 | 0 | 0 |
_aQuantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases / _cedited by Honghui Zhou, Diane R. Mould. |
| 264 | 1 |
_aHoboken, NJ : _bWiley, _c2019. |
|
| 300 | _a1 online resource. | ||
| 336 |
_atext _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 500 | _a"John Wiley & Sons Inc."--tp verso. | ||
| 504 | _aIncludes bibliographical references and index. | ||
| 520 | _a"Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher. | ||
| 588 | _aDescription based on print version record and CIP data provided by publisher. | ||
| 650 | 1 | 2 |
_aAutoimmune Diseases _xdrug therapy _9407 |
| 650 | 1 | 2 |
_aProteins _xtherapeutic use _9408 |
| 650 | 2 | 2 |
_aProteins _xpharmacokinetics _9409 |
| 650 | 2 | 2 |
_aProtein Engineering _xmethods _9410 |
| 650 | 2 | 2 |
_aModels, Theoretical _9411 |
| 700 | 1 |
_aZhou, Honghui, _eeditor. _9412 |
|
| 700 | 1 |
_aMould, Diane R. _q(Diane Renee), _d1960- _eeditor. _9413 |
|
| 776 | 0 | 8 |
_iPrint version: _tQuantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases _bFirst edition. _dHoboken, NJ : Wiley, [2019] _z9781119289197 _w(DLC) 2018051418 |
| 906 |
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