Abstract:

Chronic kidney disease (CKD) is a growing problem in Sub-Saharan Africa and this may be attributed to an increased burden of diabetes and hypertension in the region. Dyslipidaemia with its resultant atherosclerosis in patients with chronic kidney disease is associated with an increased risk of ischemic heart diseases and cerebrovascular diseases which predisposes them to recurrent acute heart attack and strokes. We aimed to determine the patterns lipid abnormalities and associated risk factors among CKD patients at BMC

This was a cross-sectional study that was conducted at Bugando Medical Centre for CKD patients that attended dialysis between January to September 2022. Data was collected from EHMS. Data were coded and entered into SPSS software version 20 for management and analysis. We described our results using proportions (%) for categorical data and means or median for continuous variables according to distribution Predictors with significant p- value was assessed using Pearson’s correlation for predictors, and a P value < 0.05 was considered significant.

100 patients’were included in this study. The prevalence of dyslipidaemia was 91%. Triglyceride was elevated in 12% of the patients, reduced HDL in 90% of the patients and 8% of patients with elevated total cholesterol and LDL. Majority of patients (67%) had Reduced HDL only pattern of dyslipidaemia, followed by a combination of reduced HDL and elevated triglyceride which accounted 13% of the cases. We found an association between having a comorbidity and dyslipidaemia (p-value <0.05)

Dyslipidaemia is prevalent in CKD patients who are on haemodialysis, regular monitoring of blood lipids and early treatment and prophylaxis may decrease the risk.