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455: Resistance Patterns and Clinical Predictors of Pediatric Bacteremia at a Tanzanian Hospital

By: Contributor(s): Material type: TextTextPublisher number: Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tz Language: English Series: ; Critical Care Medicine Volume 43 Issue 12 Publication details: Mwanza, Tanzania: LWW & Catholic University of Health and Allied Sciences [CUHAS – Bugando] 2015/12/1 Description: Pages 115Summary: Methods: This retrospective chart review evaluated all blood cultures performed in pediatric inpatients aged 0–12 over 1 year at a Tanzanian hospital. Positive cultures and resistance patterns were recorded. Charts were reviewed and compared on a cohort of positives and negatives using chi-square and Fisher’s exact tests. Given the study’s exploratory nature and small sample size, all p-values< 0.25 were reported for hypothesis-generating purposes. Results: A total of 585 blood cultures were reviewed from 523 patients; 51 cultures were positive (20 gram positive, 31 gram negative), indicating a bacteremia prevalence of 8.7%. Of those tested against the first line regimen of ampicillin and gentamicin, 60%(14/23) were resistant. Of those tested against the second line regimen of Ceftriaxone, 75%(3/4) were resistant. Of the gram-positives, 75%(15/20) were Staph Aureus. Of these, 33%(5/15) were Methicillin
Item type: RESEARCH ARTICLES
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RESEARCH ARTICLES MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO NFIC RA1202 -1 RA1202
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Methods: This retrospective chart review evaluated all blood cultures performed in pediatric inpatients aged 0–12 over 1 year at a Tanzanian hospital. Positive cultures and resistance patterns were recorded. Charts were reviewed and compared on a cohort of positives and negatives using chi-square and Fisher’s exact tests. Given the study’s exploratory nature and small sample size, all p-values< 0.25 were reported for hypothesis-generating purposes.

Results: A total of 585 blood cultures were reviewed from 523 patients; 51 cultures were positive (20 gram positive, 31 gram negative), indicating a bacteremia prevalence of 8.7%. Of those tested against the first line regimen of ampicillin and gentamicin, 60%(14/23) were resistant. Of those tested against the second line regimen of Ceftriaxone, 75%(3/4) were resistant. Of the gram-positives, 75%(15/20) were Staph Aureus. Of these, 33%(5/15) were Methicillin

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