Contents:

Renal Hamodynamics and Sodium Chloride Excretion

Sodium Chloride Excretion

Function of Discrete Nephron Segments

Clinical Aspects of Immune Renal Disease

Diseases That Commonly Present as Nephrotic Syndrome

Glomerular Involvement in Systemic Immune Diseases

Acute Renal Failure and Toxic Nephropathy

Renal Consequences of Tumors

Polyphosphoinositides and Diacylglycerol

Renal Ischemia and Anoxia

Cells in Isolated Nephron Segments

Sodium Excretion Diuretics and Renal Prostaglandins

Eicosanoids and Renal Disease

Hypertension Prostaglandins and Thromboxane

Clinical Studies of Distal Acidification

Parathyroid Hormone

Calcitonin

Calicum Nephrolithiasis

Renal Osteodystrophy

Recent Advances in the Role of the Renal Nervous System

The ReninAngiotensin System

Renal Cell Carcinoma

The Uremic Syndrome

The Muscles and Joints

The Hemopoietic System

The Nervous System

Nutritional Assessment and Monitoring of Protein Intake

Nutrition and Renal Transplantation

Quantitation of Treatment

BloodMembrane Interaction and FirstUse Syndromes

Reuse

Renal Transplantation

Immunosuppression

Aspects of Specific Drugs in Patients with Renal Disease

Nephrotoxicity of Therapeutic Agents

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Volume 4 of Contemporary Nephrology summarizes major advances in 16 different areas of nephrology during the years 1985 and 1986. Major changes in the composition of the Editorial Board and authorship of the different chapters have occurred in this volume. Six distinguished contributors have retired from the Editorial Board. They include Dr. Zalman A. Agus, Philadelphia; Dr. Robert Anderson, Denver; Dr. Eli Friedman, Brooklyn; Dr. Richard Glassock, Torrance, California; Dr. James Schafer, Birmingham, Alabama; and Dr. Gordon Williams, Bos ton. We are grateful to them for their outstanding contributions to the of this series and for their advice and suggestions as first three volumes members of the Editorial Board. They certainly deserve substantial credit for the success of this series. Seven outstanding academicians have joined the Board. They in clude Dr. Vito M. Campese, Professor of Medicine at the University of Southern California, who contributed the chapter on "Recent Advances in the Role of the Renal Nervous System and Renin in Hypertension"; Dr. William G. Couser, Professor of Medicine and Head of the Division of Nephrology at the University of Washington in Seattle ("Immunologic Aspects of Renal Disease"); Dr. Garabed Eknoyan, Professor of Medicine and Vice Chairman of the Department of Medicine at Baylor College of Medicine ("The Uremic Syndrome"); Dr. H. David Humes, Associate Professor of Medicine and Chief of the Nephrology Section at the Uni versity of Michigan Medical School, Veterans Administration Medical Center ("Acute Renal Failure and Toxic Nephropathy"); Dr. Common terms and phrases: acid acidosis activity acute renal failure aldosterone alterations amiloride angiotensin antibody apical atrial bicarbonate Biochem Biol calcitriol calcium cell membrane cellular changes chloride chronic renal failure Clin clinical collecting tubule concentration cortical culture decreased dialysis distal dogs effect enzyme epithelia factor filtration fluid flux gallbladder glomerular glomerulonephritis hemodialysis hemodynamics hormone hypercalcemia hypertension immune increased indomethacin infusion inhibition inhibitor intake intracellular intravenous ischemia ischemic isolated Kidney Int levels lipid liver mechanism mesangial metabolism mitochondrial natriuretic nephritis Nephron nephropathy normal osmolality parathyroid patients perfused permeability PGE2 PGI2 phosphate phospholipid Physiol plasma pores prostaglandin prostaglandin synthesis protein proximal tubule rabbit rat kidney reabsorption receptors reduced release renal blood flow renal disease renal function renal prostaglandin renin response role secretion serum sodium excretion solute solvent drag stimulation studies suggested sulindac syndrome therapy tissue transepithelial tubular tubuloglomerular feedback tumor TxA2 uremic urinary vascular vitamin vitro volume water transport