Effectiveness of Honey as an antibacterial agent against Methicillin resistant and susceptible Staphylococcus aureus at Bugando Medical Center in Mwanza, Tanzania
Material type:
TextPublisher number: Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz:www.bugando.ac.tzLanguage: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2021 Description: x; 19 Pages; Includes ReferencesSubject(s): Summary: Abstract:
Background: S. aureus have acquired effective antimicrobial resistance against numerous antibiotics such as penicilins. Studies are reporting the availability of alternative, safer and effective antimicrobials that is, honey against both MSSA and MRSA. Specifically, this study aim at assessing the mean zone of inhibition, minimum inhibitory concentration and bactericidal/bacteriostatic activity of honey.
Methodology: The study was a laboratory-based experimental study conducted in the CUHAS Microbiology laboratory from May to June, 2021 on 46 archived isolates, 31 of which were MRSA and the remaining were MSSA. The laboratory techniques involved were disk diffusion method, well diffusion method and broth-dilution method. Data was collected by using Microsoft Excel and STATA 13.0 software was used for analysis.
Results: The mean (±SD) zone of inhibition of honey from stinging bees against MSSA and MRSA was 9.87 ±1.19 and 8.68 ±1.73 respectively. The mean (±SD) zone of inhibition of honey from singles bees against MSSA and MRSA was 19.33 ±2.22 and 18.90 ±2.53. MIC was seen at 100% concentration of honey. Honey from stinging bees showed bacteriostatic activity against MRSA and bactericidal against MSSA. Honey from stingless bees showed bactericidal activity against MASSA and MRSA.
Conclusion: Hence, it can be conducted that honey is effective as an antibacterial agent against MSSA and MRSA.
| Item type | Current library | Collection | Status | Barcode | |
|---|---|---|---|---|---|
| UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD2431 |
Abstract:
Background: S. aureus have acquired effective antimicrobial resistance against numerous antibiotics such as penicilins. Studies are reporting the availability of alternative, safer and effective antimicrobials that is, honey against both MSSA and MRSA. Specifically, this study aim at assessing the mean zone of inhibition, minimum inhibitory concentration and bactericidal/bacteriostatic activity of honey.
Methodology: The study was a laboratory-based experimental study conducted in the CUHAS Microbiology laboratory from May to June, 2021 on 46 archived isolates, 31 of which were MRSA and the remaining were MSSA. The laboratory techniques involved were disk diffusion method, well diffusion method and broth-dilution method. Data was collected by using Microsoft Excel and STATA 13.0 software was used for analysis.
Results: The mean (±SD) zone of inhibition of honey from stinging bees against MSSA and MRSA was 9.87 ±1.19 and 8.68 ±1.73 respectively. The mean (±SD) zone of inhibition of honey from singles bees against MSSA and MRSA was 19.33 ±2.22 and 18.90 ±2.53. MIC was seen at 100% concentration of honey. Honey from stinging bees showed bacteriostatic activity against MRSA and bactericidal against MSSA. Honey from stingless bees showed bactericidal activity against MASSA and MRSA.
Conclusion: Hence, it can be conducted that honey is effective as an antibacterial agent against MSSA and MRSA.
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