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Prevalence of Placental Malaria and Uptake of Intermittent Preventive Therapy with Sulphadoxamine Pyrimethamine among Pregnant Women Attending Maternity Ward in Geita District.

By: Contributor(s): Material type: TextTextPublisher number: Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz: www.bugando.ac.tzLanguage: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2020Description: ix; 44 Pages; Includes ReferencesSubject(s): Summary: Abstract: Background: Malaria infection during pregnancy is associated with high risk of both maternal and perinatal morbidity and mortality as it can lead miscarriage, premature delivery, low birth weight, and perinatal death. Thus why, WHO currently recommends in all areas with moderate to high malaria transmission in Africa, intermittent preventive treatment during pregnancy with sultadoxamine-pyrimethamine, as part of antenatal care services that one should receive at least three doses of SP during her pregnancy. Tanzania have adopted the policy and the current upgraded regime is based on four doses of SP on ANC visit. This study was aimed to asses uptake of IPT-SP and the prevalence of placental malaria. Methodology: This was analytical cross-sectional descriptive study design, was done at Geita district in two selected health facility involving delivering woman at Geita district hospital and Katoro rural health center from June to July aiming to assess the prevalence of placental malaria and uptake of IPTp-SP study will involve any pregnant woman delivering at Geita district and Katoro rural health centre, concerted to participate in this study and woman who was resident of Geita district throughout the pregnancy period. Results: Of 160 delivery women at Katoro health centre, (5%) did not receive and dose, (13.1%) received one dose, (29.4%) received two dose, (43.1%) received three and only (9.4%) receives the recommended four or more doses of IPTp-SP, the overall prevalence of malaria in pregnancy by placental RDT, peripheral and placental smears was 15%, 20% and 28.1% respectively, the uptake of ≥4 doses of SP during pregnancy was significantly associated with ≥four ANC visits attended by the women (p=0.001). The uptake of ≥four doses of SP was associated with reduced odds of having placental malaria compared to <four doses. Conclusion: The uptake of ≥ four doses of IPTp-SP is low in the present study area (9.4%) of 160 participants. Placental parasitaemia is prevalent and receipt of ≥ four doses of IPTp-SP reduced the odds of placental parasitaemia. Thus, increased efforts towards scale-up and continuous evaluation of IPTp-SP efficacy is recommend. Keywords: Sulphadoxine-pyrimethamine, intermittent treatment, placental malaria.
Item type: UNDERGRADUATE DISSERTATIONS
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UNDERGRADUATE DISSERTATIONS MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO NFIC 1 UD1018
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Abstract:

Background: Malaria infection during pregnancy is associated with high risk of both maternal and perinatal morbidity and mortality as it can lead miscarriage, premature delivery, low birth weight, and perinatal death. Thus why, WHO currently recommends in all areas with moderate to high malaria transmission in Africa, intermittent preventive treatment during pregnancy with sultadoxamine-pyrimethamine, as part of antenatal care services that one should receive at least three doses of SP during her pregnancy. Tanzania have adopted the policy and the current upgraded regime is based on four doses of SP on ANC visit. This study was aimed to asses uptake of IPT-SP and the prevalence of placental malaria.

Methodology: This was analytical cross-sectional descriptive study design, was done at Geita district in two selected health facility involving delivering woman at Geita district hospital and Katoro rural health center from June to July aiming to assess the prevalence of placental malaria and uptake of IPTp-SP study will involve any pregnant woman delivering at Geita district and Katoro rural health centre, concerted to participate in this study and woman who was resident of Geita district throughout the pregnancy period.

Results: Of 160 delivery women at Katoro health centre, (5%) did not receive and dose, (13.1%) received one dose, (29.4%) received two dose, (43.1%) received three and only (9.4%) receives the recommended four or more doses of IPTp-SP, the overall prevalence of malaria in pregnancy by placental RDT, peripheral and placental smears was 15%, 20% and 28.1% respectively, the uptake of ≥4 doses of SP during pregnancy was significantly associated with ≥four ANC visits attended by the women (p=0.001). The uptake of ≥four doses of SP was associated with reduced odds of having placental malaria compared to <four doses.

Conclusion: The uptake of ≥ four doses of IPTp-SP is low in the present study area (9.4%) of 160 participants. Placental parasitaemia is prevalent and receipt of ≥ four doses of IPTp-SP reduced the odds of placental parasitaemia. Thus, increased efforts towards scale-up and continuous evaluation of IPTp-SP efficacy is recommend.

Keywords: Sulphadoxine-pyrimethamine, intermittent treatment, placental malaria.

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