Predictors of Survival in Preterm Neonates Exposed to Antenatal Corticosteroids at Bugando Medical Centre.
Material type:
TextPublisher number: Phone: +255 28 298 3384 Fax: +255 28 298 3386 Email: vc@bugando.ac.tz Website: www.bugando.ac.tzLanguage: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS - Bugando] : ©02.09.2019Description: viii; 19 Pages; Includes References and AppendicesSubject(s): Summary: Abstract:
Background: Preterm birth is the leading cause of perinatal and neonatal mortality and of approximately 10.6 million children under five who die each year worldwide, close to 4 million are new born infants. The main reasons for neonatal deaths worldwide are infections (36%), prematurity (28%), and birth asphyxia (23%). A single course of antenatal corticosteroids treatment had become the standard of care for women at risk of imminent or anticipated preterm delivery, particularly before 32-34 weeks gestation by improving lung maturation. Several factors predict the survival rate in preterm neonates exposed to antenatal corticosteroids which are birth weight, gestational age, neonatal infection, symptoms of respiratory distress syndrome, temperature, and maternal factors such as mode of delivery, maternal infections, dose received and mothers age.
Objective: This study investigated the predict survival rate in preterm neonates exposed to antenatal corticosteroids and prevalence of their survival.
Method: A retrospective cross section was employed. The files of premature neonates and either mothers were reviewed and data was analysed using STATA version 13.
Results/discussion: Among 167 files reviewed; 53 (31.7%) died and 114 (68.3%) survived. The survival rate of preterm neonates with birth weight ≥150g was significantly greater compared to those with birth weight <1500g with p<0.001. Whereas survival rate in preterm neonates with gestation age of <34 weeks was lower compared to those with gestation age ≥34 weeks with p=0.041. The survival rate in preterm neonates who had symptoms of RDS was also lower compared to those who had no symptoms of RDS with p=0.003. Other factors such as gender, temperature, mode of delivery and dose received had no significant association with survival rate.
Conclusion: The survival rate was greater in preterm neonates exposed to antenatal corticosteroids. Despite of using antenatal corticosteroids to improve the survival rate in preterm neonates, the factors that significantly predicted the survival rate were birth weight, gestational age and symptoms of RDS.
| Item type | Current library | Collection | Status | Barcode | |
|---|---|---|---|---|---|
| UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD0884 |
Abstract:
Background: Preterm birth is the leading cause of perinatal and neonatal mortality and of approximately 10.6 million children under five who die each year worldwide, close to 4 million are new born infants. The main reasons for neonatal deaths worldwide are infections (36%), prematurity (28%), and birth asphyxia (23%). A single course of antenatal corticosteroids treatment had become the standard of care for women at risk of imminent or anticipated preterm delivery, particularly before 32-34 weeks gestation by improving lung maturation. Several factors predict the survival rate in preterm neonates exposed to antenatal corticosteroids which are birth weight, gestational age, neonatal infection, symptoms of respiratory distress syndrome, temperature, and maternal factors such as mode of delivery, maternal infections, dose received and mothers age.
Objective: This study investigated the predict survival rate in preterm neonates exposed to antenatal corticosteroids and prevalence of their survival.
Method: A retrospective cross section was employed. The files of premature neonates and either mothers were reviewed and data was analysed using STATA version 13.
Results/discussion: Among 167 files reviewed; 53 (31.7%) died and 114 (68.3%) survived. The survival rate of preterm neonates with birth weight ≥150g was significantly greater compared to those with birth weight <1500g with p<0.001. Whereas survival rate in preterm neonates with gestation age of <34 weeks was lower compared to those with gestation age ≥34 weeks with p=0.041. The survival rate in preterm neonates who had symptoms of RDS was also lower compared to those who had no symptoms of RDS with p=0.003. Other factors such as gender, temperature, mode of delivery and dose received had no significant association with survival rate.
Conclusion: The survival rate was greater in preterm neonates exposed to antenatal corticosteroids. Despite of using antenatal corticosteroids to improve the survival rate in preterm neonates, the factors that significantly predicted the survival rate were birth weight, gestational age and symptoms of RDS.
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