Prevalence and Associated Factors of Adverse Drugs Reaction Related Hospital Admission Among Patients Attending Muhimbili National Hospital; Cross Sectional Study.
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TextPublisher number: Wurzburg Road 35, BMC Premises, Post Code: 33102: P. O. Box 1464, Mwanza – Tanzania: Phone: +255 28 298 3384: Fax: +255 28 298 3386: Email: vc@bugando.ac.tz : www.bugando.ac.tzLanguage: English Language: Kiswahili Publication details: Mwanza, Tanzania: Catholic University of Health and Allied Sciences [CUHAS – Bugando] : ©2019Description: x; 22 Pages; Includes ReferencesSubject(s): Summary: Abstract:
Background: Adverse drug reactions (ADR) are appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. ADR are reportedly a common cause of morbidity and mortality worldwide.
Methodology: This was retrospective hospital study. The study was conducted at Muhimbili National hospital (MHN) in Dar es Salaam at the drug information department (DI).
Results and discussion: The study included 383 patients with adverse drug reactions between 2018 and 2019, and data was filled in data collection tool and then analyzed using STATA 13. In this study a total of 142 (37.1%; 95%CI: 32.2-41.9) patients were found to have severe ADR. The finding of severe ADR was independently correlated to older age than 40 years (OR: 2.6; 95%CI: 1.54-4.2; p<0.001), and use of antibiotics (OR: 2.7; 95%CI: 1.4-4.9; p=0.002).
Conclusion and recommendation: There is high prevalence of ADR and is highly associated with Age and the use of antibiotics. Most of the ADR related hospital admission are preventable and require several measures to be taken so as to improve the patients’ health outcome.
| Item type | Current library | Collection | Status | Barcode | |
|---|---|---|---|---|---|
| UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD0849 |
Abstract:
Background: Adverse drug reactions (ADR) are appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. ADR are reportedly a common cause of morbidity and mortality worldwide.
Methodology: This was retrospective hospital study. The study was conducted at Muhimbili National hospital (MHN) in Dar es Salaam at the drug information department (DI).
Results and discussion: The study included 383 patients with adverse drug reactions between 2018 and 2019, and data was filled in data collection tool and then analyzed using STATA 13. In this study a total of 142 (37.1%; 95%CI: 32.2-41.9) patients were found to have severe ADR. The finding of severe ADR was independently correlated to older age than 40 years (OR: 2.6; 95%CI: 1.54-4.2; p<0.001), and use of antibiotics (OR: 2.7; 95%CI: 1.4-4.9; p=0.002).
Conclusion and recommendation: There is high prevalence of ADR and is highly associated with Age and the use of antibiotics. Most of the ADR related hospital admission are preventable and require several measures to be taken so as to improve the patients’ health outcome.
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