Abstract:

Background: Pyelonephritis, kidney stones and urosepsis are some of the complications of urinary tract infections (UTI), increasing rates of morbidity and mortality to this common disease across the world. The descriptions of patterns, pathogens, risk factors and antimicrobial resistance profiles for UTI is well described in tertiary and some regional hospitals across the country. This study aim at determining patterns of pathogenic bacteria causing UTI among patients in various district hospitals in Mwanza-Tanzania.

Methods: This cross sectional analytical study was conducted among 226 patients in various district hospitals in Mwanza-Tanzania. Pre-tested data collection tool was used to collect information from study participants. Urine specimen were collected in sterile containers and then transported to Microbiology laboratory within 2 hours of collection for processing adhering to standard operating procedures (SOPs). Data was cleaned and coded using Microsoft excels spreadsheet and analysis were done using STATA (StataCorp LLC, USA) version 13.

Significance: This study expanded ongoing efforts on creating evidence based management of patients with UTI in tertiary and regional hospitals to district hospitals, so as to have comprehensive interventional measures.

Results: Out of 138 participants, 77(87.5) had positive culture results of which 11(12.5%) had dual growth, resulting into a total of 88(64.23%) isolates, NBG samples were 50(36.23%).

Conclusion: Approximately 74(69.81%) of women with clinical features of UTI, had laboratory confirmed UTI with predominance of E.coli and Klebsiella pneumoniae isolates and most of these isolates were ESBL producers.