Seroprevalence of Brucella SPP and Associated Factors Among Pregnant Women Attending Antenatal Care at Sengerema Designated District Hospital.
Material type:
Item type | Current library | Collection | Status | Barcode | |
---|---|---|---|---|---|
UNDERGRADUATE DISSERTATIONS | MWALIMU NYERERE LEARNING RESOURCES CENTRE-CUHAS BUGANDO | NFIC | 1 | UD0806 |
Abstract:
Background: Brucellosis is among the neglected zoonotic disease implicating to cause public health concern. It remains to be endemic particularly in resource limited countries including Tanzania. The role of Brucella spp and its magnitude in animals has well documented unlike in human population. Despite the potential ability of Brucella spp to cause devastating pregnancy outcomes such as preterm birth, abortion, fetal death, and low birth weight in human there is limited data on magnitude of disease among pregnant women in Tanzania.
Objective: This study aimed to determine the seroprevalence of Brucella spp. and its associated factors among pregnant women attending antenatal care at Sengerema designated district hospital Mwanza Tanzania.
Methods: This was a cross sectional hospital based study involving 251 pregnant women attending Sengerema designated district hospital for antenatal care from May to June 2019. Information including socio-demographic data was collected using pre-tested structured data collection tool. Blood samples was collected and plasma was tested qualitatively by agglutination test method. Data was analyzed by STATA version 13 as per study objective.
Results: The mean age and mean gestation age of enrolled women was 26.61±6.69 years and 24.35±7.19 weeks respectively. Overall seroprevalence of Brucella spp. was 74/251 (29.48%, 95% CI: 23.7-35.2) with 8/251 (3.19%, 95%CI: 0.9-5.3) being both B. abortus and B. melitensis seroprevalence respectively. On multivariate logistic regression analysis only consumption of unpasteurized milk was significantly associated with Brucella spp. seroprevalence (OR: 1.78 CI: 1.00-3.15 P=0.048).
Conclusion: Overall Brucella spp. seropositivity is high among pregnant women in Sengerema necessitating the need for adequate preventive and control measure to be taken possibly of including it in the antenatal screening services.
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